Mujagic M, Flury W, Descoeudres C, Montandon A, Debrunner H U
Schweiz Med Wochenschr. 1977 Oct 22;107(42):1487-92.
By means of a photon densitometer utilizing a 125I-source, bone mineral content was measured in 15 chronic renal failure patients on conservative management, 46 patients on maintenance hemodialysis and 20 patients after renal transplantation. The determinations were made at 4 sites in both radius and tibia. In patients with chronic renal failure on conservative treatment the bone mineral content did not differ significantly from that in normals. Patients on hemodialysis showed a low bone mineral content in 61 percent of females and 53 percent of males. Especially low values were obtained from 5 females who had undergone bilateral nephrectomy. After renal transplantation all female patients showed low values, whereas 50 percent of male patients showed decreased values. No correlations were found between bone mineral content and serum parameters (calcium, phosphate, alkaline phosphatase, creatinine), duration of renal failure, hemodialysis treatment or steroid medication.
通过使用125I源的光子密度计,对15例接受保守治疗的慢性肾衰竭患者、46例维持性血液透析患者和20例肾移植术后患者进行了骨矿物质含量测量。测量部位为双侧桡骨和胫骨的4个位点。接受保守治疗的慢性肾衰竭患者的骨矿物质含量与正常人相比无显著差异。血液透析患者中,61%的女性和53%的男性骨矿物质含量较低。特别是5例接受双侧肾切除术的女性患者骨矿物质含量值极低。肾移植术后,所有女性患者骨矿物质含量值均较低,而50%的男性患者骨矿物质含量值下降。未发现骨矿物质含量与血清参数(钙、磷、碱性磷酸酶、肌酐)、肾衰竭持续时间、血液透析治疗或类固醇药物治疗之间存在相关性。