Cosnes J, Laurent-Puig P, Baumer P, Bellanger J, Gendre J P, Le Quintrec Y
Service de Gastroentérologie, Hôpital Rothschild, Paris.
Ann Gastroenterol Hepatol (Paris). 1988 Jan-Feb;24(1):7-12.
The nutritional condition of 100 patients with radiation chronic enteritis was studied and compared with that of a consecutive series of 80 patients hospitalized for digestive disorders. The parameters which were measured (body weight, muscular measurement, triceps skinfold creatinine/height index, albumin, transferrin, cholesterol, lymphocytosis), were all significantly lower in patients with radiotherapy enteritis. Anthropometric parameters and lymphocytes were the most affected. The severity of the denutrition was unrelated to the duration of the radiotherapy, the presence of an associated post-radiotherapy involvement of the colon or the urinary tract, a neoplastic recurrence, possible past-history of small bowel surgery; on the contrary, it was related to the extension of actinic lesions on the small bowel and to the presence of subocclusive manifestations. The subsequent evolution at 6 months was most often complicated or unfavorable in patients presenting a severe denutrition. Therefore, denutrition is frequent and severe in the course of post-radiotherapy chronic enteritis and is associated with a more guarded prognosis.
对100例放射性慢性肠炎患者的营养状况进行了研究，并与连续收治的80例因消化系统疾病住院的患者进行了比较。所测量的参数（体重、肌肉测量值、三头肌皮褶肌酐/身高指数、白蛋白、转铁蛋白、胆固醇、淋巴细胞增多症）在放射性肠炎患者中均显著较低。人体测量参数和淋巴细胞受影响最大。营养不良的严重程度与放疗持续时间、放疗后结肠或泌尿道是否存在相关累及、肿瘤复发、既往小肠手术史无关；相反，它与小肠光化性病变的范围以及亚闭塞表现的存在有关。在6个月时，严重营养不良的患者其后续病情演变大多复杂或预后不佳。因此，放疗后慢性肠炎病程中营养不良很常见且严重，并且与预后较差相关。
