干预方案对伴发抑郁的糖尿病患者血糖控制变化的效果：一项随机对照研究的荟萃分析。

Effectiveness of intervention program on the change of glycaemic control in diabetes with depression patients: A meta-analysis of randomized controlled studies.

机构信息

Department of Psychiatric, Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China.

Department of Psychological Behavior, Guangdong Sanjiu Brain Hospital, Guangzhou, China.

出版信息

Prim Care Diabetes. 2021 Jun;15(3):428-434. doi: 10.1016/j.pcd.2021.01.006. Epub 2021 Feb 5.

DOI:10.1016/j.pcd.2021.01.006

PMID:33551333

Abstract

AIM

The glycaemic control of diabetes with depression was inconsistent from randomized controlled studies. This meta-analysis aimed to explore the effectiveness of intervention methods in diabetes with depression.

METHODS

This study systematically searched electronic databases (PubMed, EBSCO, Elsevier, Springer, Wiley, and Cochrane) for studies published up to August 17, 2020. Standardized mean difference (SMD) and 95%CI were used to evaluate the effectiveness of interventions on HbA1c. Heterogeneity was estimated using the I statistic. Begg's test was used to assess the possible publication bias among studies.

RESULTS

Twelve studies of 2444 cases were included in this study. The overall SMD is -0.22 and 95%CI -0.33 to -0.10 in 0-6 months of intervention group. The I and P were 18.4% and 0.26. There are no publication bias tested (z = 0.37, P = 0.72).

CONCLUSION

Cognitive behavioral therapy and mindful self-compassion might be effective method to improve glycaemic control of diabetes with depression in 0-6 months.

摘要

目的

伴有抑郁的糖尿病患者的血糖控制情况在随机对照研究中并不一致。本荟萃分析旨在探讨针对伴抑郁的糖尿病患者的干预方法的有效性。

方法

本研究系统地检索了电子数据库（PubMed、EBSCO、Elsevier、Springer、Wiley 和 Cochrane），检索时间截至 2020 年 8 月 17 日。采用标准化均数差（SMD）和 95%CI 评估干预措施对糖化血红蛋白（HbA1c）的有效性。采用 I ² 统计量评估研究间的异质性。采用 Begg 检验评估研究间是否存在可能的发表偏倚。