Department of Neurosciences, College of Medicine - Philippine General Hospital, University of the Philippines Manila, PH.
Department of Medicine, College of Medicine - Philippine General Hospital, University of the Philippines Manila, PH.
Tremor Other Hyperkinet Mov (N Y). 2021 Jan 20;11:2. doi: 10.5334/tohm.576.
There is limited literature documenting hemichorea-hemiballism (HCHB) resulting from co-infection of toxoplasmosis and tuberculosis (TB) in acquired immunodeficiency syndrome (AIDS). Toxoplasmic abscess is the most common cause while TB is a rare etiology.
We describe a 24-year-old male with AIDS-related HCHB as the presentation of cerebritis on the right subthalamic nucleus and cerebral peduncle from intracranial toxoplasma and TB co-infection. Antimicrobials and symptomatic therapy were given. Marked improvement was seen on follow-up.
HCHB may be the initial presentation of intracranial involvement of this co-infection in the setting of AIDS and is potentially reversible with timely management.
Hemichorea-hemiballismus (HCHB) may be an initial presentation of intracranial involvement of concomitant toxoplasmosis and tuberculosis causing focal cerebritis in the contralateral subthalamic nucleus and cerebral peduncle, particularly in the setting of human immunodeficiency virus infection.Acquired immunodeficiency syndrome-related HCHB is potentially reversible with timely diagnosis and treatment.
有限的文献记录了艾滋病患者同时感染弓形体病和结核分枝杆菌（TB）导致的偏侧舞蹈-投掷症（HCHB）。弓形虫脓肿是最常见的病因，而 TB 是一种罕见的病因。
我们描述了一例 24 岁男性，因颅内弓形体和 TB 合并感染导致右侧丘脑底核和大脑脚脑炎，出现艾滋病相关 HCHB。给予了抗菌药物和对症治疗。随访时明显改善。
HCHB 可能是 AIDS 患者颅内弓形体和 TB 合并感染的首发表现，及时治疗可能逆转。
HCHB 可能是同时发生的弓形体病和结核分枝杆菌导致对侧丘脑底核和大脑脚局灶性脑炎的颅内受累的首发表现，尤其是在人类免疫缺陷病毒感染的情况下。艾滋病相关 HCHB 及时诊断和治疗可能逆转。
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