Gastaut J L, Nicoli F, Somma-Mauvais H, Bartolomei F, Dalecky A, Bruzzo M, Dhiver C, Gastaut J A
Service de Neurologie, Hôpital Ste-Marguerite, Marseille.
Rev Neurol (Paris). 1992;148(12):785-8.
The authors report two cases of hemichorea-hemiballism revealing a toxoplasmic abscess in the subthalamic nucleus during AIDS. Despite the great frequency of this opportunistic infection such cases are exceptional. This rarity seems to be explained by the frequent association of other lesions of the basal ganglia which may prevent the movement disorders. Nevertheless an hemichorea-hemiballism in young people must suggest a cerebral toxoplasmosis. Finally a symptomatic treatment is often necessary; in these cases the use of sodium valproate must be considered, this drug being able to induce a clinical improvement.
作者报告了两例偏侧舞蹈症-偏侧投掷症病例,这些病例显示在艾滋病期间丘脑底核出现了弓形虫脓肿。尽管这种机会性感染很常见,但此类病例却很罕见。这种罕见性似乎可以通过基底神经节其他病变的频繁关联来解释,这些病变可能会阻止运动障碍的发生。然而,年轻人出现偏侧舞蹈症-偏侧投掷症必须怀疑脑弓形虫病。最后,对症治疗往往是必要的;在这些病例中,必须考虑使用丙戊酸钠,这种药物能够使临床症状得到改善。