Clinic of Gynecology and Obstetrics, Clinical University Center Sarajevo, Sarajevo, Bosnia and Herzegovina.
Department of Gynecology, Obstetrics and Reproductive Medicine, School of Medicine, Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina.
J Perinat Med. 2020 Dec 22;49(4):455-459. doi: 10.1515/jpm-2020-0544. Print 2021 May 26.
The aim of this prospective study was to correlate the Doppler ultrasonography of the uterine arteries with the Kurjak Antenatal Neurodevelopmental Test (KANET), to investigate the effect of uterine artery flow assessed by the Doppler on fetal behavior.
A population of 80 pregnant women in the second trimester of pregnancy was included for uterine artery Doppler (UAD) assessment. The investigation group consisted of 40 women with abnormal UAD, while the control group consisted of 40 women with normal UAD. The inclusion criteria for the investigated group were: gestation above 20 weeks, and an abnormal finding of Doppler ultrasonography of the uterine arteries. All patients underwent a KANET test and were followed up to the end of their pregnancy.
There was a statistically significant difference in the average score of KANET tests between the two groups (9.20±3.32 vs. 13.55±2.21; p=0.001). In the first group, an abnormal flow on the side of the placenta affected the score of the KANET test (B=11.948; p=0.005), while abnormal flow on the opposite side did not affect the score of the KANET test (p>0.05). Physiological flow had no effect on the KANET test in the control group (p>0.05).
Abnormal flow affects the value of the KANET score, and can be used as one of the parameters in evaluation of probable fetal neurodevelopmental disorders.
本前瞻性研究旨在探讨子宫动脉多普勒超声与 Kurjak 产前神经发育测试（KANET）的相关性，研究子宫动脉血流评估对胎儿行为的影响。
纳入 80 例妊娠中期孕妇进行子宫动脉多普勒（UAD）评估。观察组为 40 例 UAD 异常孕妇，对照组为 40 例 UAD 正常孕妇。观察组纳入标准为：妊娠 20 周以上，子宫动脉多普勒超声异常。所有患者均行 KANET 检查，并随访至妊娠结束。
两组 KANET 测试平均评分存在统计学差异（9.20±3.32 与 13.55±2.21；p=0.001）。第一组胎盘侧异常血流影响 KANET 测试评分（B=11.948；p=0.005），而对侧异常血流不影响 KANET 测试评分（p>0.05）。对照组生理血流对 KANET 测试无影响（p>0.05）。
异常血流会影响 KANET 评分值，可作为评估胎儿神经发育障碍的参数之一。
