Frailty in Ageing (FRIA) Research Department, Vrije Universiteit Brussel, Belgium.
Gerontology Department, Vrije Universiteit Brussel, Belgium.
J Appl Gerontol. 2022 Feb;41(2):430-440. doi: 10.1177/0733464821991007. Epub 2021 Feb 8.
To analyze prefrailty's relationship with limitations in activities of daily living (ADLs) and restrictions in social participation.
Robust (Fried 0/4; = 214; = 82.3 years [ ±2.1]) and prefrail (Fried 1-2/4; = 191; = 83.8 years [ ±3.2]) community-dwelling older individuals were included. Frailty scores were obtained from weight loss, exhaustion, gait speed, and grip strength. A total disability index (DI) expressed dependency for basic (b-), instrumental (i-), and advanced (a-)ADLs. Total participation score, being a member, total number of memberships, being a board member, level of participation, membership over time, volunteering, and formal participation represented social participation.
Logistic regression retained age (OR = 1.224; 95% CI = [1.122, 1.335]), sex (OR = 3.818; 95% CI = [2.437, 5.982]), and a-ADL-DI (OR = 1.230; 95% CI = [1.018, 1.486]) as variables significantly related to prefrailty (68.3%; χ = 68.25; = 3; < .001).
Subtle limitations in a-ADLs, higher age, and being a man were associated with prefrailty, revealing the possible role of personal and culturally related a-ADLs as red flags for (pre)frailty.
分析虚弱前期与日常生活活动（ADL）受限和社会参与受限的关系。
纳入了身体健壮（Fried 0/4；n=214；年龄=82.3 岁[±2.1]）和虚弱前期（Fried 1-2/4；n=191；年龄=83.8 岁[±3.2]）的社区居住的老年人。衰弱评分来自体重减轻、疲劳、步态速度和握力。总残疾指数（DI）表示对基本（b-）、工具性（i-）和高级（a-）ADL 的依赖。总参与评分、成员身份、总会员人数、董事会成员身份、参与水平、随时间的会员资格、志愿服务和正式参与代表社会参与。
逻辑回归保留了年龄（OR=1.224；95%CI=[1.122,1.335]）、性别（OR=3.818；95%CI=[2.437,5.982]）和 a-ADL-DI（OR=1.230；95%CI=[1.018,1.486]）作为与虚弱前期显著相关的变量（68.3%；χ²=68.25；自由度=3；P<0.001）。
细微的 a-ADL 受限、较高的年龄和男性与虚弱前期有关，这揭示了个人和文化相关的 a-ADL 可能作为（预）虚弱的预警信号的作用。
