Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Harvard Medical School, Boston, Massachusetts; Head and Neck Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Pract Radiat Oncol. 2021 Jul-Aug;11(4):e395-e401. doi: 10.1016/j.prro.2021.01.009. Epub 2021 Feb 6.
Cardiac metastases pose clinical challenges for radiation oncologists given the need to balance the benefit of local therapy against the risks of cardiac toxicity in the setting of cardiac motion, respiratory motion, and nearby organs at risk. Stereotactic magnetic resonance-guided adaptive radiation therapy has recently become more commonly used, conferring benefits in tumor visualization for setup, real-time motion management monitoring, and enabling plan adaptation for daily changes in tumor and/or normal tissues. Given these benefits, we developed and implemented a workflow for local treatment of metastatic disease within the heart using stereotactic magnetic resonance-guided adaptive radiation therapy.
心脏转移瘤给放射肿瘤学家带来了临床挑战，因为需要在心脏运动、呼吸运动和邻近的危险器官的情况下，平衡局部治疗的益处与心脏毒性的风险。立体定向磁共振引导自适应放疗最近越来越多地被使用，在设置方面提高了肿瘤可视化的益处，实时运动管理监测，并能够针对肿瘤和/或正常组织的日常变化进行计划调整。考虑到这些益处，我们开发并实施了一种使用立体定向磁共振引导自适应放疗治疗心脏内转移性疾病的局部治疗工作流程。
