Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA.
Department of Neurosurgery, University of Vermont, Burlington, Vermont, USA.
World Neurosurg. 2021 May;149:26-31. doi: 10.1016/j.wneu.2021.01.139. Epub 2021 Feb 5.
Transient cardiac dysfunction, or Takotsubo cardiomyopathy, is a well-known complication among patients presenting with neurologic insult, who are described as having takotsubo syndrome. This condition is commonly associated with aneurysmal subarachnoid hemorrhage but has also been described in patients after cerebral surgery or in those with ischemic stroke, seizure, and traumatic brain injury. Current evidence suggests that cardiac dysfunction in these patients is a result of increases in catecholamines that are induced by supraphysiologic levels of sympathetic activity. The cardiac injury is typically reversible and carries a good prognosis, but secondary complications may arise if the diagnosis is not recognized early.
一过性心功能障碍，亦称心尖球形综合征，是因神经系统损伤而就诊的患者中一种熟知的并发症，这些患者被描述为患有心尖球综合征。这种情况通常与颅内动脉瘤性蛛网膜下腔出血相关，但也有患者在经历脑部手术后，或患有缺血性脑卒中、癫痫和外伤性脑损伤时出现。现有证据表明，这些患者的心功能障碍是由于交感神经活动的超生理水平引起的儿茶酚胺增加所致。心脏损伤通常是可逆的，预后良好，但如果早期未识别出该诊断，可能会出现继发性并发症。
