外用5-氟尿嘧啶溶液治疗疣——临床经验与经皮吸收
Topical 5-fluorouracil solution in the treatment of warts--clinical experience and percutaneous absorption.
作者信息
Senff H, Reinel D, Matthies C, Witts D
机构信息
Department of Dermatology, Federal Armed Forces Hospital, Hamburg, West Germany.
出版信息
Br J Dermatol. 1988 Mar;118(3):409-14. doi: 10.1111/j.1365-2133.1988.tb02436.x.
Abstract
Disseminated warts in six patients were pre-treated with topical 5-fluorouracil solution three times daily for 5 consecutive days. Curettage was then carried out under local anaesthesia. During pre-treatment less than 0.1% of the dose applied was absorbed through the skin. The warts had not reappeared in 5 of the 6 patients at follow-up 1 year later.
摘要
6例播散性疣患者，先局部外用5-氟尿嘧啶溶液，每日3次，连续5天进行预处理。然后在局部麻醉下进行刮除术。预处理期间，经皮肤吸收的药量不到用药量的0.1%。1年后随访时，6例患者中有5例疣体未再出现。
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