哥伦比亚波哥大 Raoultella 分离株患者的临床和微生物学特征。

Clinical and microbiological characteristics of patients with Raoultella spp. isolation in Bogotá, Colombia.

机构信息

Especialización en Medicina Interna, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.

Servicio de Medicina Interna, Fundación Cardioinfantil, Bogotá, Colombia.

出版信息

Med Clin (Barc). 2022 Jan 7;158(1):20-23. doi: 10.1016/j.medcli.2020.10.024. Epub 2021 Feb 6.

DOI:10.1016/j.medcli.2020.10.024

PMID:33558064

Abstract

INTRODUCTION

Raoultella spp. is a gram-negative bacillus with increasing clinical importance due to the development of multi-drug resistance and because it has been reported as a cause of invasive infection. The risk of infection increases if comorbidities present such as diabetes mellitus and malignancies.

METHODS

Descriptive study of clinical and microbiological characteristics in adult patients with Raoultella spp. isolation, treated at a fourth-level hospital in Bogotá, Colombia, between 2015 and 2020.

RESULTS

61 patients with isolation of Raoultella spp., 51 were considered infection and 10, colonization. The associated comorbidities were hypertension (n=26, 42.6%), heart failure (n=19, 31.1%) and diabetes mellitus (n=18, 29.5%). AmpC resistance patterns were found in 10 samples (16.4%) and KPC in 3 (4.9%).

CONCLUSIONS

Raoultella spp. is of clinical importance due to its isolation in immunocompromised patients with multiple comorbidities and due to the increase in multi-resistant strains.

摘要

简介

随着多药耐药性的发展以及作为侵袭性感染的原因的报道，越来越多的临床重要性使得鲁氏菌属（Raoultella spp.）成为革兰氏阴性杆菌。如果存在合并症，如糖尿病和恶性肿瘤，感染的风险会增加。

方法

对 2015 年至 2020 年间在哥伦比亚波哥大的一家四级医院接受治疗的成人患者中分离出的鲁氏菌属（Raoultella spp.）的临床和微生物学特征进行描述性研究。

结果

61 例患者分离出鲁氏菌属（Raoultella spp.），其中 51 例被认为是感染，10 例是定植。相关的合并症有高血压（n=26，42.6%）、心力衰竭（n=19，31.1%）和糖尿病（n=18，29.5%）。在 10 个样本中发现了 AmpC 耐药模式（16.4%），3 个样本中发现了 KPC（4.9%）。