Acta Chim Slov. 2020 Mar;67(1):203-211.
A novel bismuth(III) complex with 2-amino-3-carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene (ACTT) as a ligand have been synthesized. The novel complex was characterized on the basis of its IR, NMR, elemental analysis and MS spectral data. It was found that the ligand behaves as a monodentate chelating agent and bonds to the metal ion through the nitrogen atom of the amino group to form the [BiIII(ACTT)6]Cl3 complex. The new complex compound displayed significant antimicrobial activity (MIC = 8-32 µg/mL) against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Shigella flexneri, Candida albicans, Candida tropicalis and Cryptococcus neoformans.
一种以 2-氨基-3-甲氧基-4,5,6,7-四氢苯并[b]噻吩（ACTT）为配体的新型三价铋配合物已经被合成。根据其红外、核磁共振、元素分析和质谱谱数据对该新型配合物进行了表征。结果表明，该配体作为单齿螯合配体，通过氨基中的氮原子与金属离子键合，形成[BiIII(ACTT)6]Cl3配合物。新型配合物对枯草芽孢杆菌、金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌、福氏志贺菌、白色念珠菌、热带假丝酵母和新型隐球菌均具有显著的抗菌活性（MIC=8-32μg/mL）。
