Selcuk University, Faculty of Medicine, Department of Neurosurgery, Konya, Turkey.
Turk Neurosurg. 2021;31(2):254-260. doi: 10.5137/1019-5149.JTN.30786-20.2.
To compare the histological and angiographic measurements of the basilar artery in an experimental rabbit subarachnoid hemorrhage model.
The basilar artery was measured using both histological and angiographic methods in experimental subarachnoid hemorrhage (SAH) and vasospasm rabbit models. New Zealand white rabbits were randomly categorized into two groups: control and SAH groups. The SAH group rabbits were operated on to create an experimental SAH. Both groups were examined angiographic and histological methods.
On comparing the two methods, angiographic and histopathological measurements of the basilar artery were similar in the control group. However, in the SAH group, the difference between the angiographic and histopathological measurement methods was significant. Histopathological measurements of the basilar artery were lower than angiographic measurements, and the difference was statistically significant. In the angiographic method, although there was a marked decrease in basilar artery measurements in the SAH group, the differences between the groups was not statistically significant. However, in the histopathological method, measurement differences between the control and SAH groups were statistically significant.
Histopathological measurements were shown to be more sensitive than angiographic methods in demonstrating cerebral vasopasm in experimental SAH rabbit models.
比较实验性兔蛛网膜下腔出血模型基底动脉的组织学和血管造影测量值。
采用组织学和血管造影方法测量实验性蛛网膜下腔出血（SAH）和血管痉挛兔模型中的基底动脉。新西兰白兔随机分为两组：对照组和 SAH 组。SAH 组兔进行手术以建立实验性 SAH。两组均进行血管造影和组织学检查。
比较两种方法，对照组基底动脉的血管造影和组织病理学测量值相似。然而，在 SAH 组，血管造影和组织病理学测量方法之间的差异具有统计学意义。基底动脉的组织学测量值低于血管造影测量值，差异具有统计学意义。在血管造影方法中，尽管 SAH 组基底动脉测量值明显下降，但组间差异无统计学意义。然而，在组织病理学方法中，对照组和 SAH 组之间的测量差异具有统计学意义。
组织病理学测量在显示实验性 SAH 兔模型中的脑血管痉挛方面比血管造影方法更敏感。
