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[吸烟作为腰椎全椎间盘置换术后患者晚期异位骨化的危险因素]

[Smoking as a risk factor of advanced heterotopic ossification in patients after lumbar total disk arthroplasty].

作者信息

Konovalov N A, Stepanov I A, Beloborodov V A, Korolishin V A, Brinyuk E S

机构信息

Burdenko Neurosurgery Center, Moscow, Russia.

Irkutsk State Medical University, Irkutsk, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2021;85(1):19-27. doi: 10.17116/neiro20218501119.

DOI:10.17116/neiro20218501119
PMID:33560617
Abstract

UNLABELLED

Smoking is an obvious risk factor of adverse events in early and long-term postoperative period after spine surgery including lumbar total disk arthroplasty. Objective. To study the effect of smoking on clinical and radiological outcomes after lumbar total disk arthroplasty.

MATERIAL AND METHODS

A single-center retrospective observational cohort study was performed. We have analyzed medical records of patients who underwent single-level lumbar total disk arthroplasty for degenerative disease.

RESULTS

The study included 57 medical records of respondents. The examined medical records were divided into two groups - smokers (=26) and non-smokers (=31). There were no significant between-group differences in clinical outcomes. Incidence of adverse events was similar too. Kaplan-Meier event-free survival was similar in both groups. There were no significant between-group differences in X-ray data. Development of heterotopic ossification after lumbar total disk arthroplasty was more active in smokers.

CONCLUSION

Smoking has no significant effect on clinical and radiological outcomes in patients after single-level after lumbar total disk arthroplasty. On the other hand, smoking significantly increases formation of heterotopic ossification after lumbar total disk arthroplasty.

摘要

未标注

吸烟是包括腰椎全椎间盘置换术在内的脊柱手术后早期和长期术后不良事件的一个明显风险因素。目的:研究吸烟对腰椎全椎间盘置换术后临床和影像学结果的影响。

材料与方法

进行了一项单中心回顾性观察队列研究。我们分析了因退行性疾病接受单节段腰椎全椎间盘置换术患者的病历。

结果

该研究纳入了57份受访者的病历。所检查的病历分为两组——吸烟者(=26)和非吸烟者(=31)。临床结果在组间无显著差异。不良事件的发生率也相似。两组的Kaplan-Meier无事件生存率相似。X线数据在组间无显著差异。腰椎全椎间盘置换术后异位骨化的发生在吸烟者中更为活跃。

结论

吸烟对单节段腰椎全椎间盘置换术后患者的临床和影像学结果无显著影响。另一方面,吸烟显著增加腰椎全椎间盘置换术后异位骨化的形成。

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