Division of Critical Care Medicine.
Department of Anesthesiology, Virginia Commonwealth University Health System.
Curr Opin Anaesthesiol. 2021 Apr 1;34(2):168-172. doi: 10.1097/ACO.0000000000000960.
Organ transplantation remains the gold standard therapy for many end-organ diseases. The demand for donor organs continues to grow to far exceed supply. This review summarizes recent protocols, procedures, and ethics surrounding the increased utilization of donors after circulatory death for transplantation.
An increasing number of centers are utilizing donation after circulatory death, and outcomes are improving. Although outcomes from donors after brain death continue to be the primary source of donation, circulatory death outcomes continue to improve approaching the level of brain death donors.
Donation after circulatory death offers a real opportunity to narrow the supply and demand issue with organ donation. Outcomes are improving, and protocols continue to evolve.
器官移植仍然是许多终末期疾病的金标准治疗方法。对供体器官的需求持续增长,远远超过供应。本综述总结了最近关于增加使用循环死亡供体进行移植的方案、程序和伦理问题。
越来越多的中心正在使用循环死亡后捐献,并且效果正在改善。尽管脑死亡供体的效果仍然是主要的捐献来源,但循环死亡供体的效果继续改善,接近脑死亡供体的水平。
循环死亡后捐献为缩小器官捐献的供需问题提供了一个真正的机会。效果正在改善,方案也在不断发展。