Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel, affiliated to the Hebrew University, Jerusalem, Israel .
Eye Contact Lens. 2021 Jun 1;47(6):381-382. doi: 10.1097/ICL.0000000000000775.
To report a case of late-onset interface fluid syndrome (IFS) after laser-assisted in situ keratomileusis (LASIK).
A 94-year-old man was referred for evaluation because of persistent corneal edema 10 days after Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) for pseudophakic bullous keratopathy.
After an uneventful DSAEK, the patient was treated with topical antibiotics and steroids. On presentation, a well positioned and oriented DSAEK graft was observed in the right eye, yet the cornea was edematous. Applanation tonometry was normal. Anterior-segment optical coherence tomography (AS-OCT) revealed a LASIK flap with a fluid cleft beneath it. Requery confirmed that LASIK was performed 21 years ago. Topical steroids were stopped, and after 2 weeks, the cornea was clear, and AS-OCT revealed complete resolution of the interface fluid.
Even decades later, IFS should be considered as a source of corneal edema in patients after LASIK. Monitoring these patients with AS-OCT is recommended.
报告一例激光辅助原位角膜磨镶术（LASIK）后迟发性界面液综合征（IFS）。
一名 94 岁男性因假性囊泡性角膜病变行去表皮自动内皮角膜移植术（DSAEK）后 10 天出现持续性角膜水肿，被转来评估。
DSAEK 后无并发症，患者接受局部抗生素和皮质类固醇治疗。就诊时，右眼可见位置和方向良好的 DSAEK 移植物，但角膜水肿。压平眼压计正常。眼前节光学相干断层扫描（AS-OCT）显示 LASIK 瓣下有液性裂隙。进一步询问证实 21 年前曾行 LASIK。停止局部皮质类固醇治疗，2 周后角膜清亮，AS-OCT 显示界面液完全吸收。
即使是在 LASIK 多年后，IFS 也应被视为 LASIK 后患者角膜水肿的原因之一。建议对这些患者进行 AS-OCT 监测。
