Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Dermatol Online J. 2021 Jan 15;27(1):13030/qt8bz0t06p.
Blastic plasmacytoid dendritic cell neoplasm is a rare hematologic neoplasm originating from plasmacytoid dendritic cell precursors that has an aggressive disease course with typically poor prognosis. Herein, we report a man in his early twenties who presented with rapid onset of violaceous nodules and purpuric papules and macules that began on his chest before spreading to his arms, back, face, scalp, and legs. He also exhibited systemic symptoms including weight loss and night sweats. He was diagnosed with blastic plasmacytoid dendritic cell neoplasm and began treatment with aggressive multidrug therapy. Thus far his treatment has resulted in complete resolution of his cutaneous manifestations.
原始滤泡性淋巴瘤是一种起源于原始滤泡树突状细胞的罕见血液系统肿瘤，具有侵袭性疾病过程和通常较差的预后。在此，我们报告一例 20 岁出头的男性，其表现为迅速出现紫色结节和瘀点及瘀斑，最初出现在胸部，然后扩散至手臂、背部、面部、头皮和腿部。他还表现出全身症状，包括体重减轻和盗汗。他被诊断为原始滤泡性淋巴瘤，并开始接受强化多药治疗。迄今为止，他的治疗已导致其皮肤表现完全消退。
