Jamerson Emery C, Solyman Omar, Yacoub Magdi S, Abushanab Mokhtar Mohamed Ibrahim, Elhusseiny Abdelrahman M
Department of Ophthalmology, Columbia University Irving Medical Center, Edward S. Harkness Eye Institute, New York, NY 10032, USA.
Department of Ophthalmology, Research Institute of Ophthalmology, Cairo 11261, Egypt.
Vision (Basel). 2021 Feb 5;5(1):9. doi: 10.3390/vision5010009.
Glaucoma is a common and sight-threatening complication of pediatric cataract surgery Reported incidence varies due to variability in study designs and length of follow-up. Consistent and replicable risk factors for developing glaucoma following cataract surgery (GFCS) are early age at the time of surgery, microcornea, and additional surgical interventions. The exact mechanism for GFCS has yet to be completely elucidated. While medical therapy is the first line for treatment of GFCS, many eyes require surgical intervention, with various surgical modalities each posing a unique host of risks and benefits. Angle surgical techniques include goniotomy and trabeculotomy, with trabeculotomy demonstrating increased success over goniotomy as an initial procedure in pediatric eyes with GFCS given the success demonstrated throughout the literature in reducing IOP and number of IOP-lowering medications required post-operatively. The advent of microcatheter facilitated circumferential trabeculotomies lead to increased success compared to traditional <180° rigid probe trabeculotomy in GFCS. The advent of two-site rigid-probe trabeculotomy indicated that similar results could be attained without the use of the more expensive microcatheter system. Further studies of larger scale, with increased follow-up, and utilizing randomization would be beneficial in determining optimum surgical management of pediatric GFCS.
青光眼是小儿白内障手术常见且威胁视力的并发症。由于研究设计和随访时间的差异,报道的发病率有所不同。白内障手术后发生青光眼(GFCS)的一致且可重复的危险因素包括手术时年龄小、小角膜和额外的手术干预。GFCS的确切机制尚未完全阐明。虽然药物治疗是GFCS治疗的一线方法,但许多眼睛需要手术干预,各种手术方式都有其独特的风险和益处。房角手术技术包括房角切开术和小梁切开术,鉴于文献中显示小梁切开术在降低小儿GFCS患者眼压及术后所需降眼压药物数量方面取得的成功,小梁切开术作为小儿GFCS的初始手术,其成功率高于房角切开术。与传统的<180°刚性探头小梁切开术相比,微导管辅助的环形小梁切开术在GFCS中的成功率更高。两点刚性探头小梁切开术的出现表明,不使用更昂贵的微导管系统也能获得相似的结果。进行更大规模、更长随访时间且采用随机化的进一步研究,将有助于确定小儿GFCS的最佳手术管理方法。