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无晶状体性青光眼患儿的斜视手术结果。

Outcome of angle surgery in children with aphakic glaucoma.

作者信息

Bothun Erick D, Guo Yan, Christiansen Stephen P, Summers C Gail, Anderson Jill S, Wright Martha M, Kramarevsky Natalia Y, Lawrence Mary G

机构信息

Department of Ophthalmology, University of Minnesota, Minneapolis, Minnesota 55455-5501, USA.

出版信息

J AAPOS. 2010 Jun;14(3):235-9. doi: 10.1016/j.jaapos.2010.01.005. Epub 2010 Mar 11.

Abstract

PURPOSE

To investigate the outcome of trabeculotomy and/or goniotomy for pediatric aphakic glaucoma.

METHODS

Retrospective chart review of consecutive children who had congenital cataract surgery between 1990 and 2006 and required goniotomy and/or trabeculotomy for aphakic glaucoma. Treatment success was defined as postoperative intraocular pressure of <or=24 mm Hg despite topical medication use, avoidance of trabeculectomy or shunt placement, and no visually significant complications in the follow-up period. Exclusion criteria included a diagnosis of anterior segment dysgenesis, microcornea, and glaucoma at the time of cataract surgery, and follow-up less than 1 year.

RESULTS

A total of 14 eyes of 11 patients met inclusion criteria, with a mean follow-up of 4.7 years. Of theses, 2 eyes had goniotomy alone, 3 eyes had goniotomy followed by trabeculotomy, and 9 eyes had trabeculotomy alone. Mean IOP before angle surgery was 35 +/- 10 mm Hg. Mean IOP at the last recorded visit was 22 +/- 4 mm Hg (p = 0.0005). Treatment success was observed in 8 of the 14 eyes (57.1%), with a mean number of angle procedures of 1.4 per eye: 6 eyes (42.8%) were successful after a single angle surgery, each involving an initial trabeculotomy; 3 eyes (21.4%) underwent subsequent shunt placement after initial goniotomy at 6 months, 1.3 years, and 5.5 years after the last angle surgery.

CONCLUSIONS

When intraocular surgery is indicated to control IOP in pediatric aphakic glaucoma, trabeculotomy and/or goniotomy can be successful in the majority of eyes and may decrease the need for filtering and shunting procedures.

摘要

目的

探讨小梁切开术和/或前房角切开术治疗儿童无晶状体性青光眼的效果。

方法

对1990年至2006年间接受先天性白内障手术且因无晶状体性青光眼需要行前房角切开术和/或小梁切开术的连续儿童进行回顾性病历审查。治疗成功的定义为尽管使用局部药物,但术后眼压≤24 mmHg,避免行小梁切除术或分流管置入术,且随访期间无明显视力并发症。排除标准包括白内障手术时诊断为前段发育异常、小角膜和青光眼,以及随访时间少于1年。

结果

共有11例患者的14只眼符合纳入标准,平均随访4.7年。其中,2只眼仅行前房角切开术,3只眼先行前房角切开术,随后行小梁切开术,9只眼仅行小梁切开术。房角手术前平均眼压为35±10 mmHg。最后一次记录随访时的平均眼压为22±4 mmHg(p = 0.0005)。14只眼中有8只眼(57.1%)治疗成功,每只眼平均房角手术次数为1.4次:6只眼(42.8%)单次房角手术后成功,每次手术均为初始小梁切开术;3只眼(21.4%)在最后一次房角手术后6个月、1.3年和5.5年分别在初始前房角切开术后行分流管置入术。

结论

当需要行眼内手术控制儿童无晶状体性青光眼的眼压时,小梁切开术和/或前房角切开术在大多数眼中可能成功,并可能减少滤过和分流手术的需求。

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