Jin Z H, Zhao G L, Ziong S S, Kou P Y, Ma L L, Chen H T, Qi J Y, Ba Q J, Mai K
Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou, People's Republic of China.
Hepatology. 1988 Mar-Apr;8(2):371-3. doi: 10.1002/hep.1840080230.
Fourteen young Chinese marmots (Marmota bobak sibirica Radde) were randomly allocated to two groups of seven each. They were injected intrahepatically with a standard woodchuck hepatitis virus challenge pool or a negative pool, prepared from sera of woodchucks with and without woodchuck hepatitis virus infection, respectively. Marmot No. 2 in the experimental group experienced an episode of seroconversion from woodchuck hepatitis surface antigen to anti-woodchuck hepatitis antibody. Woodchuck hepatitis virus DNA was detected, and woodchuck hepatitis surface antigen particles of both spherical and filamentous forms and intact woodchuck hepatitis virus virions were found in its serum. By contrast, none of the control group animals (receiving the negative pool) produced any marker of woodchuck hepatitis virus. This suggests that young Chinese marmots can get woodchuck hepatitis virus infection.
十四只中华旱獭幼崽（Marmota bobak sibirica Radde）被随机分为两组，每组七只。分别向它们肝内注射标准土拨鼠肝炎病毒攻击混合液或阴性混合液，前者由感染和未感染土拨鼠肝炎病毒的土拨鼠血清制备而成。实验组中的2号旱獭经历了从土拨鼠肝炎表面抗原到抗土拨鼠肝炎抗体的血清转化过程。检测到土拨鼠肝炎病毒DNA，并且在其血清中发现了球形和丝状形式的土拨鼠肝炎表面抗原颗粒以及完整的土拨鼠肝炎病毒颗粒。相比之下，对照组动物（接受阴性混合液）均未产生任何土拨鼠肝炎病毒标志物。这表明中华旱獭幼崽能够感染土拨鼠肝炎病毒。
