Crespo Frank A, Ganesh Dervi, Lo Kaming, Chin Kevin, Norris Paul, Chakhtoura Nahida
Department of Obstetrics & Gynecology, Jackson Memorial Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Holtz Children's Hospital, Suite 3062, 1611 NW 12th Avenue, Miami, FL 33136, USA.
ISRN Infect Dis. 2014;2014. doi: 10.1155/2014/501729. Epub 2014 Mar 4.
To compare surgical, ultrasound guided drainage, and medical management of tuboovarian abscesses (TOA) and determine if different characteristics in patient presentation influence treatment and outcome.
Retrospective cohort study of 158 patients admitted to Jackson Memorial Hospital between 2007 and 2012 with a TOA.
Patients treated with IV antibiotics (IV) alone were hospitalized for 5.59 days (SD 2.52), IV antibiotics and US guided drainage (IV/US) were hospitalized for 9.63 days (SD 7.58), and IV antibiotics and surgery (IV/surgery) were hospitalized for 8.14 days ((SD3.9), ( < 0.001)). A total of 52 patients were readmitted with TOA; 41.8% were treated with IV; 26.9% were readmitted with IV/US; 7.1% were readmitted with IV/surgery ( < 0.022). Patients with a TOA measuring 0-8 cm were hospitalized for 5.97 days (SD 4.24), while those greater than 8 cm were hospitalized for 7.71 days ((SD 4.69), ( < 0.029)). Patients treated with a triple antibiotic regimen were hospitalized for 8.42 days (SD 5.70) versus 5.8 days (SD 3.24) when receiving an alternative regimen ( < 0.002).
Longer hospitalization in patients treated uniformly with either triple antibiotics, ultrasound guided drainage, or surgery represents a delay in optimal treatment. Tailoring treatment plans based on patient presentation may allow for shorter hospital stays and improved morbidity.
比较输卵管卵巢脓肿(TOA)的手术治疗、超声引导下引流及药物治疗,并确定患者临床表现的不同特征是否会影响治疗及预后。
对2007年至2012年间入住杰克逊纪念医院的158例TOA患者进行回顾性队列研究。
单纯接受静脉抗生素(IV)治疗的患者住院时间为5.59天(标准差2.52),接受静脉抗生素及超声引导下引流(IV/US)的患者住院时间为9.63天(标准差7.58),接受静脉抗生素及手术(IV/手术)的患者住院时间为8.14天(标准差3.9)(P<0.001)。共有52例患者因TOA再次入院;41.8%接受IV治疗;26.9%因IV/US再次入院;7.1%因IV/手术再次入院(P<0.022)。TOA直径为0至8厘米的患者住院时间为5.97天(标准差4.24),而直径大于8厘米的患者住院时间为7.71天(标准差4.69)(P<0.029)。接受三联抗生素方案治疗的患者住院时间为8.42天(标准差5.70),而接受替代方案治疗的患者住院时间为5.8天(标准差3.24)(P<0.002)。
接受三联抗生素、超声引导下引流或手术统一治疗的患者住院时间延长,这代表了最佳治疗的延迟。根据患者临床表现制定治疗方案可能会缩短住院时间并改善发病率。