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软组织注射丰臀导致的类Purtscher样视网膜病变和弥漫性肺泡出血

Purtscher-Like Retinopathy and Diffuse Alveolar Hemorrhage Caused by Soft Tissue Injection for Gluteal Augmentation.

作者信息

Huang Laura C, Williams Basil K, Ko Audrey C, Yehoshua Zohar, Alabiad Chrisfouad R

机构信息

Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA.

出版信息

J Clin Exp Ophthalmol. 2015;6(1). doi: 10.4172/2155-9570.1000402. Epub 2015 Feb 27.

DOI:10.4172/2155-9570.1000402
PMID:33564495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7869842/
Abstract

PURPOSE

To describe a rare occurrence of acute vision loss and diffuse alveolar hemorrhage following a treatment of injectable gluteal cosmetic filler.

PATIENT AND METHODS

A 20-year-old female underwent a cosmetic injection of unknown components for gluteal augmentation. Within hours she developed progressive shortness of breath secondary to diffuse alveolar hemorrhage. She presented to ophthalmology 6 weeks later with a history of bilateral decreased vision. Clinical examination revealed cotton wool spots and retinal hemorrhages. Fluorescein angiography demonstrated macular vascular pruning and an enlarged foveal avascular zone.

RESULTS

The patient was observed and vision did not improve after 8 months of follow-up.

CONCLUSION

These findings were attributed to a Purtscher-like retinopathy secondary to systemic inflammation induced by the filler and/or direct microembolization of the injected material or fat. To the best of the authors' knowledge, this is the first documented case of diffuse alveolar hemorrhage and ischemic bilateral vision loss in a patient undergoing gluteal augmentation with dermal filler.

摘要

目的

描述注射用臀肌美容填充剂治疗后罕见的急性视力丧失和弥漫性肺泡出血情况。

患者与方法

一名20岁女性接受了成分不明的美容注射以丰臀。数小时内,她因弥漫性肺泡出血出现进行性呼吸急促。6周后她因双侧视力下降史就诊于眼科。临床检查发现棉絮斑和视网膜出血。荧光素血管造影显示黄斑血管变细和中心凹无血管区扩大。

结果

对患者进行观察,随访8个月后视力未改善。

结论

这些发现归因于填充剂引起的全身炎症继发的类似Purtscher样视网膜病变和/或注射材料或脂肪的直接微栓塞。据作者所知,这是第一例记录在案的接受真皮填充剂丰臀的患者出现弥漫性肺泡出血和双侧缺血性视力丧失的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/2097638ed2e4/nihms-1607307-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/3043c5efdcfe/nihms-1607307-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/9862769b3e27/nihms-1607307-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/2097638ed2e4/nihms-1607307-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/3043c5efdcfe/nihms-1607307-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/9862769b3e27/nihms-1607307-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f6/7869842/2097638ed2e4/nihms-1607307-f0003.jpg

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本文引用的文献

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Systematic review of Purtscher's and Purtscher-like retinopathies.Purtscher 病及类似 Purtscher 视网膜病变的系统评价
Eye (Lond). 2013 Jan;27(1):1-13. doi: 10.1038/eye.2012.222. Epub 2012 Nov 23.
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Iatrogenic retinal artery occlusion caused by cosmetic facial filler injections.由美容面部填充物注射引起的医源性视网膜动脉阻塞。
Am J Ophthalmol. 2012 Oct;154(4):653-662.e1. doi: 10.1016/j.ajo.2012.04.019. Epub 2012 Jul 25.
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Angiocentric systemic granulomatosis.血管中心性系统性肉芽肿病
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ArteFill permanent injectable for soft tissue augmentation: II. Indications and applications.爱贝芙(ArteFill)永久性软组织填充剂:二、适应证和应用。
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Case report and literature review: acute pneumonitis and alveolar hemorrhage after subcutaneous injection of liquid silicone.病例报告与文献综述:皮下注射液体硅酮后发生的急性肺炎和肺泡出血
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Subcutaneous silicone injection leading to multi-system organ failure.皮下注射硅胶导致多系统器官衰竭。
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