Douglas Jennifer E, Lee John Y K, Rajasekaran Karthik
Department of Otorhinolaryngology - Head & Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Department of Neurosurgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Biomed Hub. 2020 Oct 6;5(3):210-213. doi: 10.1159/000510303. eCollection 2020 Sep-Dec.
Prostate adenocarcinoma is the most common malignancy in males in the United States and is typically highly treatable. Herein we present a case report of a male with a history of prostate adenocarcinoma previously managed with definitive radiation therapy who presented with sudden onset diplopia and examination consistent with an abducens palsy. He was ultimately found to have prostate adenocarcinoma metastatic to the clivus causing cranial neuropathy, and was referred for systemic chemotherapy and palliative Cyberknife stereotactic radiosurgery. While relatively rare, metastatic disease should be included in the differential diagnosis of atypical skull base lesions.
前列腺腺癌是美国男性中最常见的恶性肿瘤，通常具有较高的可治疗性。在此，我们报告一例有前列腺腺癌病史的男性病例，该患者先前接受了根治性放射治疗，此次因突发复视而就诊，检查发现符合外展神经麻痹。最终发现他患有转移至斜坡的前列腺腺癌，导致颅神经病变，并被转诊接受全身化疗和姑息性射波刀立体定向放射外科治疗。虽然相对罕见，但转移性疾病应纳入非典型颅底病变的鉴别诊断中。
