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COVID-19 时期的主动脉瓣狭窄:快速周转经导管主动脉瓣置换术服务的发展和结果。

Aortic stenosis in the time of COVID-19: Development and outcomes of a rapid turnaround TAVI service.

机构信息

Glenfield Hospital, University Hospitals, Leicester, Leicester, UK.

University of Leicester Department of Cardiovascular Sciences and Leicester NIHR Biomedical Research Unit, Leicester, UK.

出版信息

Catheter Cardiovasc Interv. 2021 Sep;98(3):E478-E482. doi: 10.1002/ccd.29550. Epub 2021 Feb 10.

DOI:10.1002/ccd.29550
PMID:33565703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8014719/
Abstract

The COVID-19 pandemic has resulted in the cancellation of many elective surgical procedures. This has led to reports of an increase in mortality for patients with non-Covid health conditions due to delayed definitive management. Patients with severe aortic stenosis have a high annual mortality if left untreated. These patients are at risk due to the reduced number of surgical aortic valve replacements and competition for intensive care facilities during the COVID-19 pandemic. This case series suggests that the minimally invasive transcatheter aortic valve implantation is safe to continue during the COVID-19 pandemic with adjustments to the patient pathway to minimize hospital stay and to reduce patient and staff exposure. This helps to reduce the delay of definitive treatment for patients with severe aortic stenosis.

摘要

新冠疫情导致许多择期手术被取消。这导致了因延迟确定性治疗而导致非新冠患者健康状况恶化的死亡人数增加。未经治疗的严重主动脉瓣狭窄患者每年的死亡率很高。由于新冠疫情期间外科主动脉瓣置换术数量减少以及对重症监护设施的竞争,这些患者面临风险。本病例系列表明,在新冠疫情期间,微创经导管主动脉瓣植入术是安全的,可通过调整患者路径来尽量减少住院时间并减少患者和员工暴露,从而继续进行。这有助于减少严重主动脉瓣狭窄患者的确定性治疗延迟。

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What is happening to non-covid deaths?非新冠死亡情况如何?
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2-Year Outcomes in Patients Undergoing Surgical or Self-Expanding Transcatheter Aortic Valve Replacement.接受外科或自膨式经导管主动脉瓣置换术患者的 2 年结果。
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5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial.经导管主动脉瓣置换术与主动脉瓣狭窄不可手术患者标准治疗的 5 年结果比较(PARTNER 1):一项随机对照试验。
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Transcatheter versus surgical aortic-valve replacement in high-risk patients.经导管主动脉瓣置换术与外科主动脉瓣置换术在高危患者中的比较。
N Engl J Med. 2011 Jun 9;364(23):2187-98. doi: 10.1056/NEJMoa1103510. Epub 2011 Jun 5.