Anaesthesiology and Intensive Care, Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden.
Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Crit Care Med. 2021 Mar 1;49(3):e327-e331. doi: 10.1097/CCM.0000000000004807.
The presence of tachycardia in critically ill patients is frequently used as an indication of severity of illness and to guide treatment decisions but can be influenced by body temperature, thus confounding its interpretation. There are few data available on the relationship between body temperature and heart rate in critically ill patients.
Retrospective analysis of prospectively collected data.
Mixed medical-surgical university hospital ICU.
All patients admitted to the ICU between November 2006 and August 2019.
Body temperature was recorded in the electronic medical records at least hourly, from invasive measurements (esophageal probe, indwelling urinary catheter, pulse contour cardiac output monitoring system, or pulmonary artery catheter) or manual tympanic recordings. Heart rate was monitored continuously and hourly values were recorded in the electronic medical record. Change in heart rate with change in body temperature was assessed by extracting pairs of simultaneous body temperature and corresponding heart rate measurements from the electronic medical record: 472,941 simultaneous pairs were obtained from the 9,046 patients admitted during the study period. Each 1°C increase in body temperature between 32.0°C and 42.0°C was associated with an 8.35 beats/min increase in heart rate. Crude linear regression showed an r2 of 0.855 between body temperature and heart rate. Heart rate increased more in females than in males (9.46 vs 7.24 beats/min for each 1°C, p < 0.0001); this relationship was not affected by age or adrenergic drugs. The increase in heart rate was related to the severity of organ dysfunction.
Increase in body temperature is associated with a linear increase in heart rate of 9.46 beats/min/°C in female and 7.24 beats/min/°C in male patients. These observations will help to correctly interpret heart rate values at different body temperatures and enable more accurate evaluation of other factors associated with tachycardia.
危重病患者的心动过速常被用作疾病严重程度的指标，并指导治疗决策，但可能受体温的影响，从而使其解释变得复杂。关于危重病患者体温与心率之间的关系，可用数据很少。
前瞻性收集数据的回顾性分析。
混合内科-外科大学医院 ICU。
2006 年 11 月至 2019 年 8 月期间入住 ICU 的所有患者。
体温通过电子病历至少每小时记录一次，来自侵入性测量（食管探头、留置导尿管、脉搏轮廓心输出量监测系统或肺动脉导管）或手动鼓膜记录。心率连续监测，每小时记录在电子病历中。通过从电子病历中提取体温和相应心率测量的同时对心率随体温的变化进行评估：从研究期间入住的 9046 名患者中获得了 472941 对同时体温和心率测量值。体温在 32.0°C 至 42.0°C 之间每升高 1°C，心率增加 8.35 次/分。未校正线性回归显示体温与心率之间的 r2 为 0.855。女性心率的增加高于男性（每升高 1°C 分别增加 9.46 次/分和 7.24 次/分，p<0.0001）；这种关系不受年龄或肾上腺素能药物的影响。心率的增加与器官功能障碍的严重程度有关。
体温升高与女性患者心率线性升高 9.46 次/分/°C 和男性患者心率升高 7.24 次/分/°C 相关。这些观察结果将有助于正确解释不同体温下的心率值，并能更准确地评估与心动过速相关的其他因素。
