Programa de Pós-Graduação em Medicina, Otorrinolaringologia da Universidade Federal de São Paulo - Escola Paulista de Medicina - UNIFESP, São Paulo, SP, Brasil.
Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço da Universidade Federal de São Paulo - Escola Paulista de Medicina - UNIFESP, São Paulo, SP, Brasil.
Int Braz J Urol. 2021 Jul-Aug;47(4):747-752. doi: 10.1590/S1677-5538.IBJU.2021.99.06.
To describe the otorhinolaryngological adverse effects of the main drugs used in urological practice.
A review of the scientific literature was performed using a combination of specific descriptors (side effect, adverse effect, scopolamine, sildenafil, tadalafil, vardenafil, oxybutynin, tolterodine, spironolactone, furosemide, hydrochlorothiazide, doxazosin, alfuzosin, terazosin, prazosin, tamsulosin, desmopressin) contained in publications until April 2020. Manuscripts written in English, Portuguese, and Spanish were manually selected from the title and abstract. The main drugs used in Urology were divided into five groups to describe their possible adverse effects: alpha-blockers, anticholinergics, diuretics, hormones, and phosphodiesterase inhibitors.
The main drugs used in Urology may cause several otorhinolaryngological adverse effects. Dizziness was most common, but dry mouth, rhinitis, nasal congestion, epistaxis, hearing loss, tinnitus, and rhinorrhea were also reported and varies among drug classes.
Most of the drugs used in urological practice have otorhinolaryngological adverse effects. Dizziness was most common, but dry mouth, rhinitis, nasal congestion, epistaxis, hearing loss, tinnitus, and rhinorrhea were also reported. Therefore, doctors must be aware of these adverse effects to improve adherence to the treatment and to minimize damage to the health of patients.
描述泌尿科常用药物的耳鼻喉不良影响。
使用特定描述符（副作用、不良反应、东莨菪碱、西地那非、他达拉非、伐地那非、奥昔布宁、托特罗定、螺内酯、呋塞米、氢氯噻嗪、多沙唑嗪、阿夫唑嗪、特拉唑嗪、哌唑嗪、坦索罗辛、去氨加压素）对科学文献进行了综述，检索时间截至 2020 年 4 月。从标题和摘要中手动选择英语、葡萄牙语和西班牙语撰写的手稿。将泌尿科常用药物分为 5 组，描述其可能产生的不良反应：α-受体阻滞剂、抗胆碱能药物、利尿剂、激素和磷酸二酯酶抑制剂。
泌尿科常用药物可能引起多种耳鼻喉不良影响。最常见的是头晕，但也有报道称口干、鼻炎、鼻塞、鼻出血、听力损失、耳鸣和鼻漏，不同药物类别之间存在差异。
泌尿科常用药物多数具有耳鼻喉不良影响。最常见的是头晕，但也有口干、鼻炎、鼻塞、鼻出血、听力损失、耳鸣和鼻漏等不良反应。因此，医生必须意识到这些不良反应，以提高治疗依从性，尽量减少对患者健康的损害。
