Division of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
Department of Health Services Administration, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.
JCO Oncol Pract. 2021 Feb;17(2):e168-e177. doi: 10.1200/OP.20.00541.
High-intensity care with undue suffering among patients with cancer at the end of life (EoL) is associated with poor quality of life. We examined the pattern and predictors of high-intensity care among patients with GI cancer in Puerto Rico.
This population-based study of data from the Puerto Rico Central Cancer Registry-Health Insurance Linkage Database examined patients with GI cancer who died between 2009 and 2017. EoL care intensity indicators include the following services in the last month before death: emergency room (ER) visits, hospitalizations, intensive care unit (ICU) admissions, life-extending procedures, death in an acute care setting, and the use of chemotherapy in the last 14 days. We used logistic regression models to examine factors associated with EoL care.
Four thousand six hundred twenty-nine patients with GI cancer were included in the analysis. We found that 11.0% of patients received chemotherapy, 17.3% had > 1 hospitalization, 9.3% were in the ICU, 18.0% had > 1 ER visit, 39.3% died in an acute care setting, and 8.6% received life-extending procedures. A compound indicator of the aggressiveness of care showed that 54.5% of patients had at least one of the selected aggressive indicators. The multivariable model showed that female patients, patients ≥ 60 years of age, patients enrolled in Medicaid, patients dually eligible for both Medicare and Medicaid, and patients who survived > 1 year were less likely to receive aggressive EoL care.
Our findings support the urgent need to improve EoL care in Puerto Rico. Further studies are warranted to fully understand EoL care in patients with cancer in Puerto Rico.
在生命末期(EoL),癌症患者接受过度高强度的治疗伴随较差的生活质量。我们调查了波多黎各胃肠道癌症患者高强度治疗的模式和预测因素。
这项基于人群的研究利用了波多黎各中央癌症登记处-健康保险链接数据库的数据,研究了 2009 年至 2017 年间死亡的胃肠道癌症患者。EoL 治疗强度的指标包括死亡前一个月的以下服务:急诊室(ER)就诊、住院、重症监护病房(ICU)入院、延长生命的程序、在急性护理环境中死亡以及在最后 14 天内使用化疗。我们使用逻辑回归模型来研究与 EoL 护理相关的因素。
在分析中纳入了 4629 名胃肠道癌症患者。我们发现,11.0%的患者接受了化疗,17.3%的患者住院超过 1 次,9.3%的患者进入 ICU,18.0%的患者 ER 就诊超过 1 次,39.3%的患者在急性护理环境中死亡,8.6%的患者接受了延长生命的程序。一项治疗积极性的综合指标显示,54.5%的患者至少有一个选定的积极指标。多变量模型显示,女性患者、年龄≥60 岁的患者、参加医疗补助的患者、同时符合医疗保险和医疗补助资格的患者以及存活时间超过 1 年的患者,接受积极的 EoL 治疗的可能性较低。
我们的发现支持在波多黎各急需改善 EoL 治疗。需要进一步研究以充分了解波多黎各癌症患者的 EoL 治疗情况。