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2015 年死亡前一年中,结直肠癌患者的医疗临终关怀管理和强度:法国全国观察性研究。

Management and intensity of medical end-of-life care in people with colorectal cancer during the year before their death in 2015: A French national observational study.

机构信息

Caisse Nationale d'Assurance Maladie (Cnam) - Direction de la stratégie des études et des statistiques, Paris, France.

Service de Gastroentérologie, Hôpital Avicenne AP-HP, Bobigny, France.

出版信息

Cancer Med. 2019 Nov;8(15):6671-6683. doi: 10.1002/cam4.2527. Epub 2019 Sep 25.

DOI:10.1002/cam4.2527
PMID:31553130
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6825985/
Abstract

The care pathway of patients with colorectal cancer (CRC) 1 year prior to death, their causes of death and the healthcare use, and associated expenditure remain poorly described together. People managed for CRC (2014-2015), covered by the national health insurance general scheme and who died in 2015 were selected from the national health data system. A total of 15 361 individuals (mean age: 75 years, SD: 12.5 years) were included, almost 66% of whom died in short-stay hospital (SSH), 9% in hospital at home (HaH), 4% in rehabilitation units (Rehab), 6% in skilled nursing homes (SNH), and 15% at home. At least one other cancer was identified for one-third of these people. Almost one-half of people presented cardiovascular comorbidity, 21% had chronic respiratory disease, and 13% had a neurological or degenerative disease. During the last month of life, 83% were admitted at least once to SSH, 39% had at least one emergency department admission, 17% were admitted to an intensive care unit, 15% received at least one chemotherapy session (<60 years: 27%), and 5% received oral chemotherapy. Eighty-eight percent of the 60% of individuals who received hospital palliative care (HPC) vs 75% of those without HPC were admitted to SSH at least once during the last month. Cancer was the main cause of death for 84% (SSH: 85%, home: 77%) and corresponded to CRC for 64% of them. The mean annual expenditure per person during the last year of life was €43 398 (SSH: €48 804). This study suggests a relatively high level of HPC use during the year before death for people with CRC in France. High rates of emergency department, intensive care, and chemotherapy use were observed during the last month of life. However, management is very largely SSH-based with a small proportion of deaths at home.

摘要

在患者死亡前 1 年的结直肠癌(CRC)护理路径、死亡原因、医疗保健使用情况和相关支出尚未得到全面描述。从国家卫生数据系统中选择了在全国健康保险总计划下接受 CRC 治疗(2014-2015 年)且于 2015 年死亡的人群。共纳入 15361 人(平均年龄:75 岁,标准差:12.5 岁),其中近 66%的人在短期住院(SSH)死亡,9%在家庭医院(HaH)死亡,4%在康复病房(Rehab)死亡,6%在熟练护理院(SNH)死亡,15%在家中死亡。这些人中约有三分之一还患有其他癌症。几乎一半的人患有心血管合并症,21%患有慢性呼吸道疾病,13%患有神经或退行性疾病。在生命的最后一个月,83%的人至少入住 SSH 一次,39%至少有一次急诊就诊,17%入住重症监护病房,15%至少接受一次化疗(<60 岁:27%),5%接受口服化疗。在接受医院姑息治疗(HPC)的 60%的人中,有 88%的人在生命的最后一个月至少入住 SSH 一次,而没有接受 HPC 的人中,这一比例为 75%。癌症是 84%(SSH:85%,家中:77%)死亡的主要原因,其中 64%的人死于 CRC。生命最后一年每人的年平均支出为 43398 欧元(SSH:48804 欧元)。本研究表明,法国 CRC 患者在死亡前一年接受 HPC 的比例相对较高。在生命的最后一个月观察到急诊、重症监护和化疗的使用率很高。然而,管理主要基于 SSH,只有一小部分人在家中死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf0/6825985/5b989e0664a3/CAM4-8-6671-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf0/6825985/a47796432af4/CAM4-8-6671-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf0/6825985/5b989e0664a3/CAM4-8-6671-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf0/6825985/a47796432af4/CAM4-8-6671-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf0/6825985/5b989e0664a3/CAM4-8-6671-g002.jpg

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