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北红腹锦鸡眼部畸胎样髓上皮瘤:病例报告及文献复习。

Ocular teratoid medulloepithelioma in a northern red-shouldered macaw: case report and literature review.

机构信息

Department of Veterinary Sciences, Federal University of Paraíba, Areia, Paraiba, Brazil.

School of Veterinary Medicine, Faculdade Nova Esperança-FAMENE, João Pessoa, Paraiba, Brazil.

出版信息

J Vet Diagn Invest. 2021 May;33(3):600-604. doi: 10.1177/1040638721994601. Epub 2021 Feb 10.

DOI:10.1177/1040638721994601
PMID:33568016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8120071/
Abstract

A 4-mo-old northern red-shouldered macaw () was admitted to the veterinary hospital of the Arruda Câmara Zoo, in the State of Paraiba, Brazil, for investigation of an orbital mass. Given rapid progression and lack of response to treatment, the bird was euthanized, and an autopsy was performed. Histologically, the mass consisted of a retrobulbar invasive tumor characterized by tubular and rosette-like structures, with interspersed heteroplastic tissues, such as aggregates of neuroglial cells and islands of hyaline cartilage. The tumor was immunopositive for pancytokeratin, GFAP, NSE, and S100. These findings were compatible with an ocular teratoid medulloepithelioma, a neoplasm best described in humans but also reported rarely in young cockatiels and African Grey parrots.

摘要

一只 4 月龄的北红腹锦鸡()因眼眶肿块被送至巴西帕拉伊巴州阿鲁达·卡马拉动物园的兽医医院进行检查。鉴于病情迅速进展且对治疗无反应,这只鸟被实施了安乐死,并进行了剖检。组织学上,该肿块为眶后浸润性肿瘤,具有管状和玫瑰花结样结构,伴有异质组织穿插,如神经胶质细胞聚集和透明软骨岛。肿瘤免疫组化阳性表达细胞角蛋白广谱、胶质纤维酸性蛋白、神经元特异性烯醇化酶和 S100。这些发现与眼胚细胞瘤一致,这是一种最好在人类中描述的肿瘤,但也有报道称在幼年玄凤鹦鹉和非洲灰鹦鹉中罕见发生。