Puhakka H J, Kirveskari P
Department of Otolaryngology, University Central Hospital, Turku, Finland.
J Laryngol Otol. 1988 Mar;102(3):231-4. doi: 10.1017/s0022215100104608.
In a double-blind study, 22 patients with typical globus symptoms were investigated by both otolaryngological and odontological methods. All the patients underwent thorough hematological, endoscopic and radiological examinations. They were randomly divided into a treatment group and a placebo group and underwent either simple occlusal adjust or mock adjustment, respectively. The result of occlusal adjustment was assessed immediately after completion of treatment. The effect of treatment on globus symptoms was assessed 2 to 3 months later in a double-blind study. Binomial tests showed that there was a significant association between the success of occlusal adjustment and disappearance of the globus symptom. A new name for this disease is proposed: the globus syndrome.
在一项双盲研究中，采用耳鼻喉科和牙科方法对22名有典型咽部异感症症状的患者进行了调查。所有患者均接受了全面的血液学、内镜和放射学检查。他们被随机分为治疗组和安慰剂组，分别接受单纯的咬合调整或模拟调整。治疗完成后立即评估咬合调整的结果。在一项双盲研究中，2至3个月后评估治疗对咽部异感症症状的效果。二项式检验表明，咬合调整的成功与咽部异感症症状的消失之间存在显著关联。为此病提出了一个新名称：咽部异感症综合征。
