Department of Pathology, Hospital Sant Joan de Déu, Barcelona, Spain.
Department of Pediatric Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.
Neuropathology. 2021 Apr;41(2):139-145. doi: 10.1111/neup.12713. Epub 2021 Feb 10.
An otherwise healthy eight-year-old girl presented with a mass in the soft tissue of the sacral region. The lesion was diagnosed as a vascular malformation on imaging studies, for which percutaneous sclerotherapy was attempted. The mass continued to grow and a complete resection was performed after four years. The pathological diagnosis was giant cell ependymoma (GCE). GCE is a term used to describe a rare histologic variant of ependymoma characterized by malignancy-like morphologic phenotype and indolent behavior. To the best of our knowledge, this is the first case of extra-axial soft tissue sacral GCE reported in a child.
一位看似健康的 8 岁女孩,骶区软组织出现一肿块。影像学检查诊断为血管畸形,遂行经皮硬化治疗。四年后,肿块持续增大,行完全切除术。病理诊断为巨细胞室管膜瘤(GCE)。GCE 是一种描述室管膜瘤罕见组织学变异的术语,其特征为恶性形态表型和惰性行为。据我们所知,这是首例儿童发生的轴外骶区软组织 GCE。