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椎管外骶骨软组织巨细胞室管膜瘤影响儿童:病例报告及文献复习。

Extra-axial sacral soft tissue giant cell ependymoma affecting a child: Case report and review of the literature.

机构信息

Department of Pathology, Hospital Sant Joan de Déu, Barcelona, Spain.

Department of Pediatric Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.

出版信息

Neuropathology. 2021 Apr;41(2):139-145. doi: 10.1111/neup.12713. Epub 2021 Feb 10.

Abstract

An otherwise healthy eight-year-old girl presented with a mass in the soft tissue of the sacral region. The lesion was diagnosed as a vascular malformation on imaging studies, for which percutaneous sclerotherapy was attempted. The mass continued to grow and a complete resection was performed after four years. The pathological diagnosis was giant cell ependymoma (GCE). GCE is a term used to describe a rare histologic variant of ependymoma characterized by malignancy-like morphologic phenotype and indolent behavior. To the best of our knowledge, this is the first case of extra-axial soft tissue sacral GCE reported in a child.

摘要

一位看似健康的 8 岁女孩,骶区软组织出现一肿块。影像学检查诊断为血管畸形,遂行经皮硬化治疗。四年后,肿块持续增大,行完全切除术。病理诊断为巨细胞室管膜瘤(GCE)。GCE 是一种描述室管膜瘤罕见组织学变异的术语,其特征为恶性形态表型和惰性行为。据我们所知,这是首例儿童发生的轴外骶区软组织 GCE。

相似文献

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Giant-cell ependymoma: Presentation of a case of the sacral region and literature review.
Ultrastruct Pathol. 2017 Jul-Aug;41(4):296-300. doi: 10.1080/01913123.2017.1327910. Epub 2017 Jun 13.
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Giant cell ependymoma of the thoracic spinal cord.胸髓巨细胞室管膜瘤。
Acta Neurol Belg. 2012 Mar;112(1):71-5. doi: 10.1007/s13760-012-0038-9. Epub 2012 Feb 7.

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