Charman H P, Lowenstein D H, Cho K G, DeArmond S J, Wilson C B
Department of Pathology, (Neuropathology Unit), University of California, San Francisco.
J Neurosurg. 1988 May;68(5):806-10. doi: 10.3171/jns.1988.68.5.0806.
A 65-year-old man with a history of exposure to industrial solvents developed a primary cerebral angiosarcoma in the left posterior parieto-occipital lobe. The tumor had features typical of angiosarcoma on light and electron microscopy, immunohistochemical evidence of factor VIII-related antigen produced in tumor cells, and a high labeling index with bromodeoxyuridine. The relationship of angiosarcoma to toxins and viruses is discussed.
一名有接触工业溶剂史的65岁男性在左后顶枕叶发生了原发性脑血管肉瘤。该肿瘤在光镜和电镜下具有血管肉瘤的典型特征，肿瘤细胞产生VIII因子相关抗原的免疫组化证据，以及溴脱氧尿苷的高标记指数。文中讨论了血管肉瘤与毒素和病毒的关系。
