Navaruckiene Aukse, Bridziuviene Danguole, Raudoniene Vita, Rainosalo Egidija, Ostrauskaite Jolita
Department of Polymer Chemistry and Technology, Kaunas University of Technology, Radvilenu Rd. 19, LT-50254 Kaunas, Lithuania.
Biodeterioration Research Laboratory, Nature Research Center, Akademijos Str. 2, LT-08412 Vilnius, Lithuania.
Materials (Basel). 2021 Jan 31;14(3):653. doi: 10.3390/ma14030653.
The investigation of the influence of vanillin acrylate-based resin composition on photocuring kinetics and antimicrobial properties of the resulting polymers was performed in order to find efficient photocurable systems for optical 3D printing of bio-based polymers with tunable rigidity, as well as with antibacterial and antifungal activity. Two vanillin derivatives, vanillin diacrylate and vanillin dimethacrylate, were tested in photocurable systems using phenyl bis(2,4,6-trimethylbenzoyl)phosphine oxide as a photoinitiator. The influence of vanillin acrylate monomer, amount of photoinitiator, presence and amount of dithiol, and presence of solvent on photocuring kinetics was investigated by real-time photoreometry. Polymers of different rigidity were obtained by changing the photocurable resin composition. The photocuring kinetics of the selected vanillin acrylate-based resins was comparable with that of commercial petroleum-based acrylate resins for optical 3D printing. Polymers based on both vanillin acrylates showed a significant antibacterial activity against and Vanillin diacrylate-based polymer films also demonstrated an antifungal activity in direct contact with and Vanillin diacrylate-based dual curing systems were selected as the most promising for optical 3D printing of bio-based polymers with antibacterial and antifungal activity.
为了找到用于光学3D打印具有可调刚性以及抗菌和抗真菌活性的生物基聚合物的高效光固化体系，对基于香草醛丙烯酸酯的树脂组合物对所得聚合物的光固化动力学和抗菌性能的影响进行了研究。使用苯基双(2,4,6-三甲基苯甲酰基)氧化膦作为光引发剂，在光固化体系中测试了两种香草醛衍生物，即二丙烯酸香草醛和二甲基丙烯酸香草醛。通过实时光度法研究了香草醛丙烯酸酯单体、光引发剂用量、二硫醇的存在及用量以及溶剂的存在对光固化动力学的影响。通过改变光固化树脂组合物获得了不同刚性的聚合物。所选基于香草醛丙烯酸酯的树脂的光固化动力学与用于光学3D打印的商业石油基丙烯酸酯树脂相当。基于两种香草醛丙烯酸酯的聚合物对 和 均表现出显著的抗菌活性。基于二丙烯酸香草醛的聚合物薄膜在与 和 直接接触时也表现出抗真菌活性。基于二丙烯酸香草醛的双固化体系被选为用于具有抗菌和抗真菌活性的生物基聚合物光学3D打印最有前景的体系。
