Rahi Mandeep Singh, Gunasekaran Kulothungan, Amoah Kwesi, Chowdhury Farheen, Kwon Jeff
Division of Pulmonary Diseases and Critical Care Medicine, Yale-New Haven Health Bridgeport Hospital, 267 Grant Street, Bridgeport, CT 06258, USA.
Clin Pract. 2021 Jan 29;11(1):37-42. doi: 10.3390/clinpract11010007.
Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. It may have irregular margins, cavitation, or calcifications mimicking metastasis or primary lung neoplasm. It should be considered in the differential diagnosis of pulmonary nodules or masses. In this report, we present an unusual case of incidental slow-growing lung mass in a patient with 30 pack-year smoking history, construction-based occupation. The pleural-based calcified nodule in the left upper lobe gradually increased in size over ten years without any hilar or mediastinal lymphadenopathy. For an accurate diagnosis, PET-scan and histopathological analysis through wedge resection by video-assisted thoracoscopic surgery (VATS) were done. The biopsy findings were consistent with pulmonary hyalinizing granuloma, a rare benign cause of lung mass with an excellent long-term prognosis.
肺透明变性肉芽肿（PHG）是一种病因不明的罕见良性肺部疾病。它通常表现为孤立性，有时也表现为多发性肺结节。它可能有不规则边缘、空洞形成或钙化，类似转移瘤或原发性肺肿瘤。在肺结节或肿块的鉴别诊断中应考虑到它。在本报告中，我们介绍了一例不寻常的病例，一名有30年吸烟史、从事建筑工作的患者偶然发现肺部有一个生长缓慢的肿块。左上叶胸膜下钙化结节在十年间逐渐增大，无任何肺门或纵隔淋巴结肿大。为了准确诊断，进行了PET扫描，并通过电视辅助胸腔镜手术（VATS）楔形切除进行组织病理学分析。活检结果与肺透明变性肉芽肿一致，这是一种罕见的良性肺肿块病因，长期预后良好。
