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骨骼肌慢性疼痛人群中的性功能障碍:系统评价。

Sexual Difficulties in the Population with Musculoskeletal Chronic Pain: A Systematic Review.

机构信息

Graduate School of Health, University of Technology Sydney, Sydney, Australia.

出版信息

Pain Med. 2021 Sep 8;22(9):1982-1992. doi: 10.1093/pm/pnaa451.

Abstract

OBJECTIVE

To review the current literature on the nature and prevalence of sexual difficulties in the population with chronic musculoskeletal pain, as well as to identify the biopsychosocial factors that maintain these difficulties.

DESIGN

Systematic review.

METHODS

Studies were found by using multiple electronic databases and examining reference lists. After application of inclusion and exclusion criteria, 10 studies were eligible for review. Data were extracted and characteristics were described for outcomes of interest (i.e., sexual dysfunction, pain condition, pain intensity, psychosocial factors, gender differences). Cochrane Risk of Bias was assessed for all included studies.

RESULTS

Ten studies (2,941 participants) were included in the review. Musculoskeletal conditions included low back pain and fibromyalgia. All studies examining sexual functioning found evidence of sexual difficulty among patients with chronic pain. Three studies demonstrated that sexual dysfunction was significantly greater in patients than in healthy matched controls. Nine studies found that greater pain levels significantly correlated with greater sexual dysfunction. Eight studies noted an increased prevalence of sexual difficulties in those with comorbid psychological problems. Heterogeneity between studies was identified, particularly with regard to gender outcomes. The risk-of-bias assessment also highlighted limitations in approximately half of studies.

CONCLUSIONS

This review reiterates the importance of investigating sexual functioning in the chronic musculoskeletal pain population, given the high prevalence of chronic musculoskeletal pain across all age bands. Given methodological limitations, future research should develop measures that sensitively cater to the various needs of patients with chronic pain. By modifying assessment to include biopsychosocial concerns, practitioners can tailor treatment to address transdiagnostic factors that maintain sexual dysfunction.

摘要

目的

回顾目前关于慢性肌肉骨骼疼痛人群中性功能障碍的性质和流行情况的文献,并确定维持这些困难的生物心理社会因素。

设计

系统评价。

方法

通过使用多个电子数据库并检查参考文献列表来查找研究。在应用纳入和排除标准后,有 10 项研究符合审查条件。提取数据并描述了感兴趣的结果(即性功能障碍、疼痛状况、疼痛强度、心理社会因素、性别差异)的特征。对所有纳入的研究进行了 Cochrane 偏倚风险评估。

结果

共纳入 10 项研究(2941 名参与者)。肌肉骨骼疾病包括腰痛和纤维肌痛。所有研究都发现慢性疼痛患者存在性功能障碍。三项研究表明,与健康对照组相比,患者的性功能障碍明显更严重。九项研究发现疼痛程度越高,性功能障碍越严重。八项研究指出,患有共病心理问题的患者性功能障碍的发生率更高。研究之间存在异质性,特别是在性别结果方面。偏倚风险评估还突出了大约一半研究的局限性。

结论

鉴于慢性肌肉骨骼疼痛在所有年龄段都很普遍,本综述再次强调了在慢性肌肉骨骼疼痛人群中调查性功能的重要性。鉴于方法学的限制,未来的研究应开发出更敏感地满足慢性疼痛患者各种需求的措施。通过修改评估以纳入生物心理社会问题,临床医生可以针对维持性功能障碍的跨诊断因素来调整治疗方案。

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