Department of Medicine, Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
J Infect Dis. 2021 Jun 16;223(12 Suppl 2):S222-S235. doi: 10.1093/infdis/jiaa762.
Unique compositional and functional features of the cervicovaginal microbiota have been associated with protection against and risk for sexually transmitted infections (STI). In men, our knowledge of the interaction between the penile microbiota and STI is less developed. The current state of our understanding of these microbiota and their role in select STIs is briefly reviewed, along with strategies that leverage existing findings to manipulate genital microbiota and optimize protection against STIs. Finally, we focus on major research gaps and present a framework for future studies.
宫颈阴道微生物组的独特组成和功能特征与预防和感染性传播疾病（STI）的风险有关。在男性中，我们对阴茎微生物群与 STI 之间相互作用的了解还不够充分。本文简要回顾了这些微生物群及其在某些 STI 中的作用的现有认识，以及利用现有发现来操纵生殖道微生物群并优化预防 STI 的策略。最后，我们关注主要的研究差距，并为未来的研究提出了一个框架。
