Department of Anesthesiology, School of Medicine, Yale University, New Haven, CT.
Yale Center for Analytical Sciences, Department of Biostatistics, School of Public Health, Yale University, New Haven, CT.
Clin J Pain. 2021 May 1;37(5):366-371. doi: 10.1097/AJP.0000000000000923.
Adequate pain control after total hip arthroplasty is essential for patient satisfaction and surgical outcome.
A retrospective study with before and after design was performed in 210 elective total hip arthroplasty patients. The control group (N=132) received spinal anesthesia with periarticular injection (PAI) and the treatment group (N=78) received transmuscular quadratus lumborum block and lateral femoral cutaneous nerve block in addition to spinal anesthesia and PAI. The primary outcome was visual analog scale (VAS) pain score on postoperative day (POD) 1, and secondary outcomes included VAS and opioid consumption on each POD, hospitalization cost, length of stay, and discharge acuity.
The mean VAS and opioid consumption (MME) were significantly lower in the treatment group than that in the control group on POD 1, with VAS difference -1.10 (95% confidence interval, -1.64 to -0.55), false discover rate corrected (P<0.001), and MME difference -26.19 (95% confidence interval, -39.16 to -13.23, P<0.001). A significant difference was also found for both VAS (P=0.007) and opioid consumption (P=0.018) on POD 2 and for opioid consumption on POD 3 (P=0.008). Length of stay (days) in the control group versus the treatment group was 2.50±1.38 versus 1.36±0.95 (P=0.002), and the total cost of hospitalization was over 20% higher in the control group than that in the treatment group (P=0.002).
The addition of transmuscular quadratus lumborum and lateral femoral cutaneous nerve block in total hip arthroplasty provides improved analgesia indicated by lower pain scores and opioid reduction and accelerated recovery with shorter hospitalization and decreased hospitalization cost.
全髋关节置换术后充分的疼痛控制对于患者满意度和手术结果至关重要。
采用前后对照设计,对 210 例择期全髋关节置换术患者进行回顾性研究。对照组(n=132)接受椎管内麻醉联合关节周围注射(PAI),治疗组(n=78)在椎管内麻醉和 PAI 的基础上,接受竖脊肌外侧缘阻滞和股外侧皮神经阻滞。主要结局是术后第 1 天(POD)的视觉模拟评分(VAS)疼痛评分,次要结局包括每个 POD 的 VAS 和阿片类药物消耗量、住院费用、住院时间和出院能力。
治疗组患者术后第 1 天的 VAS 和阿片类药物消耗(MME)均明显低于对照组,VAS 差值为-1.10(95%置信区间,-1.64 至-0.55),错误发现率校正(P<0.001),MME 差值为-26.19(95%置信区间,-39.16 至-13.23,P<0.001)。术后第 2 天和第 3 天的 VAS(P=0.007)和阿片类药物消耗(P=0.018)以及第 3 天的阿片类药物消耗(P=0.008)也有显著差异。对照组和治疗组的住院时间(天)分别为 2.50±1.38 与 1.36±0.95(P=0.002),对照组的住院总费用比治疗组高出 20%以上(P=0.002)。
在全髋关节置换术中加入竖脊肌外侧缘阻滞和股外侧皮神经阻滞可提供更好的镇痛效果,表现为疼痛评分降低和阿片类药物用量减少,加速康复,缩短住院时间,降低住院费用。