Park Heon Jung, Park Kwan Kyu, Park Jun Young, Lee Bora, Choi Yong Seon, Kwon Hyuck Min
Department of Orthopedic Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.
Department of Orthopedic Surgery, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin 16995, Gyeonggi-do, Korea.
J Clin Med. 2022 Sep 16;11(18):5456. doi: 10.3390/jcm11185456.
This study aimed to evaluate the effect of a peripheral nerve block (PNB) on immediate postoperative analgesia and the early functional outcomes for patients who underwent total hip arthroplasty (THA). From January 2016 to August 2021, 353 patients who underwent THA were divided into two groups: the patient-controlled analgesia (PCA) group ( = 217) who received only intravenous (IV) analgesia, and others who received IV PCA and PNB (PCA + PNB group) ( = 136). After propensity score matching for age and sex, 136 patients from each group were included in the study. Primary outcomes were the visual analogue scale (VAS) at rest, activity status at postoperative 6, 24, 48 h. Secondary outcomes were functional scores by the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index, Harris Hip Score (HHS) and rescue medications used. The postoperative VAS at 6, 24, 48 h at rest and 6 h at activity were significantly lower in the PCA + PNB group ( = 0.000, 0.001, 0.000, 0.004 in order). There was no significant difference for postoperative 3-month HHS ( = 0.218), except for 3-month WOMAC index ( = 0.001). There were no significant differences for VAS between the PNB methods except femoral nerve block (FNB) and fascia iliaca compartment block (FICB) at postoperative activity 48 h ( = 0.028). There was no significant difference in the total count and amount of rescue medication ( = 0.091, 0.069) and difference in the quadriceps weakness was not noted. Therefore, PNB is beneficial for patients who undergo THA as it provides sufficient postoperative analgesia, especially during immediate postoperative resting pain without quadriceps weakness.
本研究旨在评估周围神经阻滞(PNB)对全髋关节置换术(THA)患者术后即刻镇痛及早期功能结局的影响。2016年1月至2021年8月,353例行THA的患者被分为两组:仅接受静脉(IV)镇痛的患者自控镇痛(PCA)组(n = 217),以及接受IV PCA和PNB的其他患者(PCA + PNB组)(n = 136)。在对年龄和性别进行倾向评分匹配后,每组纳入136例患者。主要结局指标为静息时视觉模拟量表(VAS)、术后6、24、48小时的活动状态。次要结局指标为西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、Harris髋关节评分(HHS)的功能评分以及使用的补救药物。PCA + PNB组术后6、24、48小时静息时及6小时活动时的VAS显著更低(依次为P = 0.000、0.001、0.000、0.004)。除3个月时的WOMAC指数外(P = 0.001),术后3个月的HHS无显著差异(P = 0.218)。除术后48小时活动时股神经阻滞(FNB)和髂筋膜间隙阻滞(FICB)外,PNB方法之间的VAS无显著差异(P = 0.028)。补救药物的总数和用量无显著差异(P = 0.091、0.069),且未发现股四头肌无力的差异。因此,PNB对行THA的患者有益,因为它能提供充分的术后镇痛,尤其是在术后即刻静息痛期间且不会导致股四头肌无力。