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99mTc-美罗芬宁肝胆闪烁显像联合 SPECT/CT 评估脾窝异位节段性肝移植中的肝功能。

99mTc-Mebrofenin Hepatobiliary Scintigraphy Combined With SPECT/CT to Assess Liver Function in Heterotopic Segmental Liver Transplantation in the Splenic Fossa.

机构信息

From the General Surgery and Transplantation Unit.

Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Bologna.

出版信息

Clin Nucl Med. 2021 Jun 1;46(6):e332-e335. doi: 10.1097/RLU.0000000000003521.

DOI:10.1097/RLU.0000000000003521
PMID:33577197
Abstract

Recent studies have shown that the inclusion of a noninvasive and low-cost functional test such as hepatobiliary scintigraphy is considered more reliable than volume alone to predict posthepatectomy liver failure especially in light of new liver regeneration techniques. We herein reported the unique case of a 40-year-old man who underwent heterotopic liver transplantation of segments 2 and 3 in the splenic fossa after splenectomy for unresectable colorectal liver metastases. 99mTc-mebrofenin hepatobiliary scintigraphy combined with SPECT/CT was performed after liver transplantation to monitor graft function and regeneration before removal of the native liver.

摘要

最近的研究表明,将非侵入性和低成本的功能测试(如肝胆闪烁扫描)纳入预测肝切除术后肝功能衰竭的评估中,比单纯依靠体积更为可靠,尤其是在采用新的肝脏再生技术的情况下。我们在此报告了一个独特的病例,一名 40 岁男性因不可切除的结直肠癌肝转移而行脾切除术,随后在脾窝内行 2 段和 3 段异位肝移植。肝移植后行 99mTc-美罗芬酸肝胆闪烁扫描,并结合 SPECT/CT,以在移除供体肝脏前监测移植物功能和再生。

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