Department of General Surgery, Ankara University School of Medicine.
Department of General Surgery, Gulhane Training and Research Hospital, Ankara, Turkey.
Medicine (Baltimore). 2021 Feb 12;100(6):e24613. doi: 10.1097/MD.0000000000024613.
Complete mesocolic excision (CME) is being performed more frequently and has recently become an established oncologic surgical method for right hemicolectomy. Despite its advantages, such as its association with early mobilization, a short hospital stay, early bowel movement, mild postoperative pain, and good cosmesis, CME is technically demanding and carries the risk of severe complications. This study aims to compare the clinical, pathological, and oncological results of open and laparoscopic right hemicolectomy with CME.The data of 76 patients who underwent right hemicolectomy with CME and high vascular ligation were reviewed retrospectively. The patients were divided into 2 groups according to whether the open or laparoscopic technique was used.Thirty-two patients underwent open right hemicolectomy, and 44 patients underwent laparoscopic right hemicolectomy. The 2 groups were similar in age, sex, American Society of Anesthesiologists class, abdominal surgical history, tumor localization, and operation time. No significant differences were found regarding the specimen length, tumor size, harvested lymph nodes, number of metastatic lymph nodes, or tumor grade. According to the Clavien-Dindo classification system, the laparoscopic group had significantly fewer complications than did the open group (11.4% vs 31.2%; P = .04). The open group had a longer postoperative hospital stay than did the laparoscopic hemicolectomy group (9.9 ± 4.7 vs 7.2 ± 3.1 days; P = .002). In addition, the groups were similar with respect to disease-free survival (P = .14) and overall survival (P = .06).The data in this study demonstrated that no differences exist between the open and laparoscopic techniques concerning pathological and oncological results. However, significantly fewer complications and a shorter length of hospital stay were observed in the laparoscopic group than in the open group. Laparoscopic right hemicolectomy with CME and central vascular ligation is a safe and feasible surgical procedure and should be considered the standard technique for right-sided colon cancer.
完整结肠系膜切除术(CME)的应用越来越频繁,最近已成为右半结肠切除术的一种标准的肿瘤外科方法。尽管 CME 具有早期活动、缩短住院时间、早期肠蠕动、术后疼痛较轻和美容效果好等优点,但它技术要求高,有发生严重并发症的风险。本研究旨在比较开腹和腹腔镜右半结肠 CME 切除术的临床、病理和肿瘤学结果。
回顾性分析了 76 例接受 CME 和高位血管结扎的右半结肠切除术患者的数据。根据是否使用开腹或腹腔镜技术,将患者分为两组。32 例患者接受开腹右半结肠切除术,44 例患者接受腹腔镜右半结肠切除术。两组患者的年龄、性别、美国麻醉医师协会(ASA)分级、腹部手术史、肿瘤定位和手术时间相似。两组在标本长度、肿瘤大小、采集的淋巴结数量、转移淋巴结数量或肿瘤分级方面无显著差异。根据 Clavien-Dindo 分类系统,腹腔镜组的并发症明显少于开腹组(11.4%比 31.2%;P=0.04)。开腹组的术后住院时间明显长于腹腔镜右半结肠切除术组(9.9±4.7 比 7.2±3.1 天;P=0.002)。此外,两组在无病生存率(P=0.14)和总生存率(P=0.06)方面相似。
本研究的数据表明,开腹和腹腔镜技术在病理和肿瘤学结果方面没有差异。然而,腹腔镜组的并发症明显少于开腹组,住院时间也明显缩短。CME 和中央血管结扎的腹腔镜右半结肠切除术是一种安全可行的手术方法,应被视为右侧结肠癌的标准技术。