Çelik Mevlüt, Mahtab Edris A F, Bogers Ad J J C
Department of Cardiothoracic Surgery, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
J Cardiovasc Dev Dis. 2021 Feb 10;8(2):16. doi: 10.3390/jcdd8020016.
The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation associated with aortopathy. The current study provides surgical clinical data on the patient characteristics and long-term survival of this less common adult purely BAV population undergoing surgical aortic valve replacement (SAVR) with concomitant aortic surgery. Adult patients with purely BAV who underwent SAVR and concomitant aortic surgery were included. Prevalence, predictors of survival, and outcomes for this patient population were analyzed. A total of 48 patients (mean age 58.7 ± 13.2 years, 33% female) with purely BAV underwent SAVR and concomitant aortic surgery between 1987 and 2016. The majority (62%) of the patients had pure aortic stenosis (AS). A total of 12 patients died. Survival was 92%, 73%, and 69% at 1, 5, and 20 years of follow-up. At 15 years of follow-up, the survival was close to that of the Dutch population, with a relative survival of 77%. Adult patients with a purely bicuspid aortic valve morphology undergoing SAVR and concomitant aortic root and/or ascending aorta present with excellent survival.
二叶式主动脉瓣（BAV）是与主动脉病变相关的最常见先天性心脏畸形。本研究提供了关于这一较少见的接受外科主动脉瓣置换术（SAVR）并同期进行主动脉手术的成年单纯BAV患者群体的患者特征及长期生存情况的外科临床数据。纳入接受SAVR并同期进行主动脉手术的成年单纯BAV患者。分析了该患者群体的患病率、生存预测因素及预后情况。1987年至2016年间，共有48例（平均年龄58.7±13.2岁，33%为女性）成年单纯BAV患者接受了SAVR并同期进行主动脉手术。大多数（62%）患者为单纯主动脉瓣狭窄（AS）。共有12例患者死亡。随访1年、5年和20年时的生存率分别为92%、73%和69%。随访15年时，生存率接近荷兰人群，相对生存率为77%。接受SAVR并同期进行主动脉根部和/或升主动脉手术的成年单纯二叶式主动脉瓣形态患者具有出色的生存率。
