Hypothermic machine perfusion before viability testing of previously discarded human livers.
作者信息
van Leeuwen Otto B, de Vries Yvonne, de Meijer Vincent E, Porte Robert J
机构信息
Department of Surgery, Section of Hepatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
出版信息
Nat Commun. 2021 Feb 12;12(1):1008. doi: 10.1038/s41467-021-21182-8.
Abstract
摘要
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Hypothermic machine perfusion before viability testing of previously discarded human livers.在对先前废弃的人体肝脏进行生存能力测试之前进行低温机器灌注。
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Transplantation of high-risk donor livers after resuscitation and viability assessment using a combined protocol of oxygenated hypothermic, rewarming and normothermic machine perfusion: study protocol for a prospective, single-arm study (DHOPE-COR-NMP trial).采用充氧低温、复温及常温和机器灌注联合方案复苏和评估供肝活力后移植高危供肝：一项前瞻性、单臂研究的研究方案（DHOPE-COR-NMP 试验）。
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Bile proteome reveals biliary regeneration during normothermic preservation of human donor livers.胆汁蛋白质组揭示了人类供体肝脏在常温保存过程中的胆管再生。
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Sequential hypothermic and normothermic machine perfusion enables safe transplantation of high-risk donor livers.序贯低温及常温机器灌注使高危供肝安全移植成为可能。
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Reply to 'Hypothermic machine perfusion before viability testing of previously discarded human livers'.对“在先前废弃的人体肝脏进行活力测试前进行低温机器灌注”的回复
Nat Commun. 2021 Feb 12;12(1):1015. doi: 10.1038/s41467-021-21183-7.
本文引用的文献
1
Transplantation of discarded livers following viability testing with normothermic machine perfusion.常温机器灌注下进行活力测试后废弃肝脏的移植。
Nat Commun. 2020 Jun 16;11(1):2939. doi: 10.1038/s41467-020-16251-3.
2
Transplantation of High-risk Donor Livers After Ex Situ Resuscitation and Assessment Using Combined Hypo- and Normothermic Machine Perfusion: A Prospective Clinical Trial.原位复苏和联合亚低温及常温机器灌注评估后高危供肝的移植：一项前瞻性临床试验。
Ann Surg. 2019 Nov;270(5):906-914. doi: 10.1097/SLA.0000000000003540.
3
Transplantation of high-risk donor livers after resuscitation and viability assessment using a combined protocol of oxygenated hypothermic, rewarming and normothermic machine perfusion: study protocol for a prospective, single-arm study (DHOPE-COR-NMP trial).采用充氧低温、复温及常温和机器灌注联合方案复苏和评估供肝活力后移植高危供肝：一项前瞻性、单臂研究的研究方案（DHOPE-COR-NMP 试验）。
BMJ Open. 2019 Aug 15;9(8):e028596. doi: 10.1136/bmjopen-2018-028596.
4
Pretransplant sequential hypo- and normothermic machine perfusion of suboptimal livers donated after circulatory death using a hemoglobin-based oxygen carrier perfusion solution.使用基于血红蛋白的氧载体灌注液对停循环死亡后捐献的非优质供肝进行移植前序贯亚低温及常温和机器灌注。
Am J Transplant. 2019 Apr;19(4):1202-1211. doi: 10.1111/ajt.15228. Epub 2019 Jan 23.
5
Biliary Bicarbonate, pH, and Glucose Are Suitable Biomarkers of Biliary Viability During Ex Situ Normothermic Machine Perfusion of Human Donor Livers.胆汁碳酸氢盐、pH 值和葡萄糖是人类供体肝脏离体常温机器灌注期间胆道活力的合适生物标志物。
Transplantation. 2019 Jul;103(7):1405-1413. doi: 10.1097/TP.0000000000002500.
6
Viability Criteria for Functional Assessment of Donor Livers During Normothermic Machine Perfusion.常温机器灌注期间供肝功能评估的生存能力标准
Liver Transpl. 2018 Oct;24(10):1333-1335. doi: 10.1002/lt.25330.
7
Observations on the ex situ perfusion of livers for transplantation.肝脏移植的体外灌流观察。
Am J Transplant. 2018 Aug;18(8):2005-2020. doi: 10.1111/ajt.14687. Epub 2018 Mar 14.
8
Hypothermic oxygenated machine perfusion reduces bile duct reperfusion injury after transplantation of donation after circulatory death livers.低温氧合机器灌注可降低脑死亡供体肝移植后胆管再灌注损伤。
Liver Transpl. 2018 May;24(5):655-664. doi: 10.1002/lt.25023. Epub 2018 Apr 6.
9
Normothermic Perfusion in the Assessment and Preservation of Declined Livers Before Transplantation: Hyperoxia and Vasoplegia-Important Lessons From the First 12 Cases.常温灌注在评估和保存移植前功能衰退肝脏中的应用：高氧血症和血管麻痹——来自前12例病例的重要经验教训
Transplantation. 2017 May;101(5):1084-1098. doi: 10.1097/TP.0000000000001661.
10
Dual hypothermic oxygenated machine perfusion in liver transplants donated after circulatory death.循环死亡后捐赠肝脏移植中的双重低温氧合机器灌注
Br J Surg. 2017 Jun;104(7):907-917. doi: 10.1002/bjs.10515. Epub 2017 Apr 10.
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