Fathi A, Hennigs A, Addo M M
Medizinische Klinik und Poliklinik, Sektion Infektiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Internist (Berl). 2021 Apr;62(4):373-378. doi: 10.1007/s00108-021-00967-5. Epub 2021 Feb 12.
The increasing development of antimicrobial resistance has been identified as one of the greatest threats to public health and is caused to a relevant extent by falsely indicated antibiotic treatment.
The main aim of this article is to identify areas in infectious disease diagnostics and treatment where overuse occurs and to provide recommendations on how to avoid it.
The authors identified current and relevant studies on the topic of medical overuse in infectious diseases via a literature search. In particular, contributions from international "less is more" initiatives were included. The focus was on areas in which a reduction of diagnostic and therapeutic measures leads to an optimization of patient outcomes.
In many cases overuse in the context of diagnostics and treatment of infectious diseases not only leads to an unnecessary financial burden on the healthcare system and is not beneficial but can also increase the risk of development of antimicrobial resistance and have adverse consequences for patients.
Correct indications as well as focused selection and adequate application of antimicrobial agents is crucial to provide the best possible medical care. Diagnostic and antibiotic stewardship measures, which should be implemented in collaboration with infectious disease specialists, can help to identify and reduce areas of overuse and misuse.
抗菌药物耐药性的不断发展已被确认为对公众健康的最大威胁之一，且在相当程度上是由抗生素治疗的错误指征所致。
本文的主要目的是确定传染病诊断和治疗中存在过度使用的领域，并就如何避免过度使用提供建议。
作者通过文献检索确定了当前关于传染病医疗过度使用这一主题的相关研究。特别纳入了国际“少即是多”倡议的相关内容。重点关注那些减少诊断和治疗措施能优化患者治疗效果的领域。
在许多情况下，传染病诊断和治疗中的过度使用不仅给医疗系统带来不必要的经济负担且并无益处，还会增加抗菌药物耐药性产生的风险，并对患者产生不良后果。
正确的用药指征以及抗菌药物的针对性选择和合理应用对于提供尽可能最佳的医疗护理至关重要。应与传染病专家合作实施的诊断和抗生素管理措施有助于识别和减少过度使用和滥用的领域。
