Department of Vascular and Endovascular Surgery, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Department of Cardiac Surgery, Heidelberg University Hospital, Heidelberg, Baden-Württemberg, Germany.
Thorac Cardiovasc Surg. 2022 Jun;70(4):314-322. doi: 10.1055/s-0040-1722732. Epub 2021 Feb 12.
The treatment of extensive thoracic/thoracoabdominal aortic pathologies with arch involvement remains a challenging task in aortic surgery. The introduction of the frozen elephant trunk (FET) technique offered a link between open surgery and thoracic endovascular aortic repair (TEVAR). Despite a decade of experience, data on the complementary use of these techniques are scant. The aim of this study was to evaluate TEVAR following FET in clinical reality.
Between November 2006 and June 2018, 20 patients (9 females; median age of 69 years) underwent endovascular second-stage completion after FET. The clinical outcomes, technical feasibility, and morphological findings were analyzed retrospectively.
Eleven of the 20 interventions were intended "rendezvous procedures" in a multistage approach; 4 were elective reinterventions, and 5 were emergency complication repairs. The median interval between FET and TEVAR was 231 days (11 days-7.4 years). The technical success rate was 100%. During a median follow-up (FU) period of 58.3 months, the overall survival rate was 95%, with one in-hospital death. Neurological complications occurred in three cases (spinal cord injury: = 1; stroke: = 2). Computed tomography angiography showed overall regression in the median diameter of the proximal descending aorta (from 57 to 48.5 mm).
TEVAR as a second-stage intervention after FET is a feasible option, with satisfactory results at medium-term FU. In extensive thoracoabdominal aortic disease without proximal landing zones, the complementary use of both techniques in a multistage approach should be considered.
涉及弓部病变的广泛胸/胸腹主动脉病变的治疗仍然是主动脉外科的一项挑战性任务。冷冻象鼻技术(FET)的引入为开放手术和胸主动脉腔内修复术(TEVAR)之间提供了联系。尽管有十年的经验,但关于这些技术互补使用的数据仍然很少。本研究旨在评估 FET 后 TEVAR 在临床实践中的应用。
2006 年 11 月至 2018 年 6 月期间,20 例患者(9 例女性;中位年龄 69 岁)在 FET 后进行了血管内二期完成。回顾性分析了临床结果、技术可行性和形态学发现。
20 例干预中有 11 例为多阶段治疗中的“会师手术”;4 例为择期再次干预,5 例为紧急并发症修复。FET 和 TEVAR 之间的中位间隔时间为 231 天(11 天-7.4 年)。技术成功率为 100%。中位随访(FU)期为 58.3 个月,总体生存率为 95%,院内死亡 1 例。3 例出现神经系统并发症(脊髓损伤:=1;中风:=2)。CT 血管造影显示近端降主动脉的平均直径总体缩小(从 57 毫米缩小至 48.5 毫米)。
FET 后作为二期干预的 TEVAR 是一种可行的选择,在中期 FU 时结果令人满意。在没有近端着陆区的广泛胸腹主动脉疾病中,应考虑在多阶段治疗中联合使用这两种技术。