Minol Jan-Philipp, Dimitrova Vanessa, Petrov Georgi, Langner Robert, Boeken Udo, Lichtenberg Artur, Akhyari Payam
Department of Cardiac Surgery, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany.
Department of Vascular and Endovascular Surgery, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany.
Thorac Cardiovasc Surg. 2022 Mar;70(2):106-111. doi: 10.1055/s-0041-1723973. Epub 2021 Feb 12.
With this study we aimed to analyze if the separate consideration of body mass index (BMI) could provide any superior predictive values compared with the established risk scores in isolated minimally invasive mitral valve surgery (MIMVS). This might facilitate future therapeutic decision-making, e.g., regarding the question surgery versus transcatheter mitral valve repair (TMVr).
We assessed the relevance of BMI in non-underweight patients who underwent isolated MIMVS. The risk predictive potential of BMI for mortality and several postoperative adverse events was assessed in 429 consecutive patients. This predictive potential was compared with that of European System for Cardiac Outcome Risk Evaluation II (EuroSCORE II) and the Society of Thoracic Surgeons score (STS score) using a comparative receiver operating characteristic curve analysis.
BMI was a significant numeric predictor of wound healing disorders ( = 0.001) and proved to be significantly superior in case of this postoperative adverse event compared with the EuroSCORE II ( = 0.040) and STS score ( = 0.015). Except for this, the predictive potential of BMI was significantly inferior compared with that of the EuroSCORE II and STS score for several end points, including 30-day ( = 0.029 and = 0.006) and 1-year ( = 0.012 and = 0.001) mortality.
Therefore, we suggest that, in the course of decision-making regarding the right treatment modality for non-underweight patients with isolated mitral valve regurgitation, the sole factor of BMI should not be given a predominant weight.
通过本研究,我们旨在分析在孤立性微创二尖瓣手术(MIMVS)中,与既定风险评分相比,单独考虑体重指数(BMI)是否能提供任何更高的预测价值。这可能有助于未来的治疗决策,例如,关于手术与经导管二尖瓣修复(TMVr)的问题。
我们评估了BMI在接受孤立性MIMVS的非体重过轻患者中的相关性。在429例连续患者中评估了BMI对死亡率和几种术后不良事件的风险预测潜力。使用比较性受试者工作特征曲线分析,将这种预测潜力与欧洲心脏结局风险评估系统II(EuroSCORE II)和胸外科医师协会评分(STS评分)进行比较。
BMI是伤口愈合障碍的重要数字预测指标(P = 0.001),并且在这种术后不良事件方面,与EuroSCORE II(P = 0.040)和STS评分(P = 0.015)相比,被证明具有显著优势。除此之外,对于包括30天(P = 0.029和P = 0.006)和1年(P = 0.012和P = 0.001)死亡率在内的几个终点,BMI的预测潜力与EuroSCORE II和STS评分相比显著较差。
因此,我们建议,在为非体重过轻的孤立性二尖瓣反流患者选择正确治疗方式的决策过程中,不应将BMI这一单一因素作为主要考量。