Department of Pharmacy, University of North Carolina Medical Center, Chapel Hill, NC, USA.
Am J Health Syst Pharm. 2021 Mar 31;78(8):736-742. doi: 10.1093/ajhp/zxab040.
Obtaining an accurate medication history from patients on hospital admission is a priority in pharmacy practice. Timely and accurate histories are imperative as they may help determine the etiology of illness and prevent medication errors. We conducted a quality improvement project to assess the accuracy of alternate-source medication histories obtained for critically ill patients who were delirious or mechanically ventilated at the time of intensive care unit admission.
Included patients were 18 years of age or older, admitted to the medical intensive care unit from August 2017 through January 2018, and had a medication history obtained from a family member or outpatient pharmacy due to active delirium or mechanical ventilation. Patients were directly interviewed after resolution of delirium or extubation. Discrepancies between the initial and follow-up histories were documented and categorized using the National Coordinating Council for Medication Error Reporting and Prevention (NCC MERP) Index for Categorizing Medication Errors.
Forty patients were included. One hundred four discrepancies were documented, with a median of 2 discrepancies per patient. The most common types of discrepancies were addition (51.9%), followed by omission (24.0%). NCC MERP index category A (51%) was the most common error classification identified.
Discrepancies between initial and follow-up medication histories occurred at a frequent rate in delirious or mechanically ventilated patients; however, these discrepancies tended to be of low risk severity.
在患者入院时获取准确的用药史是药学实践的重中之重。及时、准确的用药史至关重要,因为它有助于确定疾病的病因并预防用药错误。我们开展了一项质量改进项目,以评估在 ICU 入院时处于谵妄或机械通气状态的危重症患者的替代来源用药史的准确性。
纳入标准为 18 岁及以上,因活跃性谵妄或机械通气而从 2017 年 8 月至 2018 年 1 月从内科 ICU 入院,且用药史是从家属或门诊药房获得的患者。在患者谵妄缓解或拔管后,对其进行直接访谈。记录初始和随访用药史之间的差异,并使用国家协调委员会药物错误报告和预防(NCC MERP)索引对药物错误进行分类。
共纳入 40 例患者。共记录了 104 个差异,中位数为每个患者 2 个差异。最常见的差异类型是添加(51.9%),其次是遗漏(24.0%)。最常见的错误分类是 NCC MERP 索引 A 类(51%)。
在谵妄或机械通气患者中,初始和随访用药史之间存在频繁的差异,但这些差异往往严重程度较低。