Department of Dermatology, National Hospital Center, Nouakchott, Mauritania.
National Institute for Public Health Research, Nouakchott, Mauritania.
Trans R Soc Trop Med Hyg. 2021 Apr 14;115(4):315-319. doi: 10.1093/trstmh/traa197.
Mycetoma is a chronic, progressive and destructive inflammatory disease that affects the skin, subcutaneous and other tissues. The objective of this study was to identify all cases of mycetoma diagnosed in three health facilities in Nouakchott, Mauritania during 2016-2018.
This retrospective hospital-based study was conducted at the Dermatology, Orthopedics, Mycology and Pathology departments of the National Hospital Center of Nouakchott, the Military Hospital of Nouakchott and the National Institute for Research in Public Health of Nouakchott.
Eighty-seven patients were included in this study. They comprised 65 male patients (74.71%) and 22 females (25.28%) with a gender ratio of 4:1. The mean age was 41.87 y and ages ranged from 14 to 70 y. The most common age group was 40-45 y (11%). The foot was the most frequently affected site seen in 60 patients (69%), followed by ankle and hand with 6 patients each (7%). In the study, 56 patients (64%) had regional lymphadenopathy. Forty-nine patients (56%) had bone involvement. Thirty-two patients (37%) had medical treatment. Twenty-seven patients (87%) received fluconazole and four patients (13%) had co-trimoxazole treatment.
The mycetoma patients seen in these three centres were mainly male farmers from rural areas. The lesions were seen mainly in the lower limbs and the majority had bone involvement radiologically.
足菌肿是一种慢性、进行性和破坏性的炎症性疾病，影响皮肤、皮下组织和其他组织。本研究的目的是确定 2016 年至 2018 年期间在毛里塔尼亚努瓦克肖特的三家医疗机构诊断的所有足菌肿病例。
这是一项在努瓦克肖特国家医院中心皮肤科、骨科、真菌学和病理学系、努瓦克肖特军事医院和努瓦克肖特国家公共卫生研究所进行的回顾性基于医院的研究。
本研究纳入了 87 名患者，包括 65 名男性患者（74.71%）和 22 名女性患者（25.28%），性别比为 4:1。平均年龄为 41.87 岁，年龄在 14 至 70 岁之间。最常见的年龄组为 40-45 岁（11%）。足部是最常见的受累部位，有 60 例（69%），其次是踝关节和手部，各有 6 例（7%）。在研究中，56 例（64%）患者有区域性淋巴结病。49 例（56%）患者有骨受累。32 例（37%）患者接受了药物治疗。27 例（87%）患者接受了氟康唑治疗，4 例（13%）患者接受了复方磺胺甲噁唑治疗。
这三个中心的足菌肿患者主要是来自农村地区的男性农民。病变主要发生在下肢，大多数患者有放射学骨受累。
