肥胖女性在运动时呼吸困难和自愿性过度通气。
Dyspnea during exercise and voluntary hyperpnea in women with obesity.
机构信息
Centre for Research in Occupational Safety and Health, Laurentian University, ON, Canada.
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and University of Texas Southwestern Medical Center, Dallas, TX, USA.
出版信息
Respir Physiol Neurobiol. 2021 May;287:103638. doi: 10.1016/j.resp.2021.103638. Epub 2021 Feb 11.
Temporal responses of ratings of perceived breathlessness (RBP) during constant-load and incremental exercise, and during voluntary hyperpnea (EVH) were examined in women with obesity. Following 6 min of constant-load (60W) cycling, 34 women rated RPB≥4 (+DOE) and 22 women rated RPB≤2 (-DOE). Both groups completed an incremental cycling test and an EVH test at 40 and 60L/min; RPB was assessed each minute of incremental cycling and at the end of each EVH trial. RPB increased with ventilation during constant-load (+DOE: R=0.86; -DOE: R=0.82) and incremental (+DOE: R=0.91; -DOE: R=0.92) exercise, but + DOE had a greater y-intercept than -DOE (60W: -0.16±1.53 vs. -0.73±0.55; incremental: -0.50±1.40 vs. -1.71±0.84). Despite matching ventilation, RPB was greater in + DOE at baseline (0.97±1.14 vs. 0.14±0.28), 40L/min (2.50±1.43 vs. 0.98±0.91), and 60L/min (3.94±2.19 vs. 2.07±1.32) during EVH. These findings show that despite linear associations between RPB and ventilation during exercise and voluntary hyperpnea, breathlessness perception at a given ventilatory demand is heightened in +DOE compared with -DOE.
肥胖女性在恒负荷和递增运动以及自主过度通气（EVH）期间感知呼吸急促（RBP）的时间反应进行了检查。在 6 分钟的恒负荷（60W）自行车运动后，34 名女性报告 RBP≥4（+ DOE），22 名女性报告 RBP≤2（- DOE）。两组均完成递增自行车测试和 40 和 60L/min 的 EVH 测试；在递增自行车运动的每一分钟和 EVH 试验结束时评估 RBP。在恒负荷（+ DOE：R=0.86；- DOE：R=0.82）和递增（+ DOE：R=0.91；- DOE：R=0.92）运动期间，RBP 随通气增加而增加，但+ DOE 的截距大于- DOE（60W：-0.16±1.53 vs. -0.73±0.55；递增：-0.50±1.40 vs. -1.71±0.84）。尽管通气匹配，但在基线时，+ DOE 的 RBP 更高（0.97±1.14 vs. 0.14±0.28），在 40L/min 时（2.50±1.43 vs. 0.98±0.91），在 60L/min 时（3.94±2.19 vs. 2.07±1.32）在 EVH 期间。这些发现表明，尽管在运动和自主过度通气期间 RBP 与通气之间存在线性关联，但与 - DOE 相比，+ DOE 在给定通气需求下的呼吸急促感知更高。
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