Murat Caner, Palandoken Merih, Kaya Irfan, Kaya Adnan
Department of Electrical and Electronics Engineering, Izmir Katip Celebi University, Izmir, Turkey.
Department of Mechanical Engineering, Eskisehir Technical University, Eskisehir, Turkey.
Electromagn Biol Med. 2021 Apr 3;40(2):286-300. doi: 10.1080/15368378.2021.1885434. Epub 2021 Feb 14.
In this paper, a radiation performance improved novel applicator is proposed which is called as reflector type microwave applicator as a part of microwave ablation (MWA) system operating at 2.45 GHz with experimentally measured bandwidth of 300 MHz in Industrial Scientific Medical (ISM) band for the local extermination of tumor with highly localized microwave power. The design principle of MW applicator is based on the structural formation of coaxial transmission line fed dielectric loaded with the metallic circular reflector for the near field energy concentration inside the tumorous tissue. To generate localized electromagnetic waves, a novel reflector type microwave applicator is designed by placing an aluminum disk near the 10 mm dielectric radiator section. The proposed applicator design has been numerically studied with finite integration technique (FIT) in CST Microwave Studio to develop the near field radiation pattern affecting the ablation level of tumorous tissue. In the light of performed numerical calculations, maximum SAR (Specific Absorption Rate) value on 1.76 g tumorous sample can be achieved to 208 W/kg under 15 W microwave power accepted by proposed probe. The experimental results confirm that proposed applicator can be utilized highly localized MWA applicator for cancer treatment hence the surface temperature of cylindrical shaped tumor sample which has the dimensions of 14.4 mm diameter and 8 mm height reaches from 25 to 68.3°C in 10 min.
本文提出了一种辐射性能得到改善的新型 applicator,它被称为反射器型微波 applicator,是微波消融(MWA)系统的一部分,该系统在 2.45GHz 下运行,在工业、科学和医疗(ISM)频段的实验测量带宽为 300MHz,用于通过高度局部化的微波功率局部消除肿瘤。微波 applicator 的设计原理基于同轴传输线馈电的介质加载结构,并带有金属圆形反射器,用于肿瘤组织内的近场能量集中。为了产生局部电磁波,通过在 10mm 介质辐射器部分附近放置一个铝盘,设计了一种新型反射器型微波 applicator。所提出的 applicator 设计已在 CST 微波工作室中采用有限积分技术(FIT)进行了数值研究,以开发影响肿瘤组织消融水平的近场辐射模式。根据进行的数值计算,在所提出的探头接受 15W 微波功率的情况下,1.76g 肿瘤样本上的最大比吸收率(SAR)值可达到 208W/kg。实验结果证实,所提出的 applicator 可作为高度局部化的 MWA applicator 用于癌症治疗,因此直径为 14.4mm、高度为 8mm 的圆柱形肿瘤样本的表面温度在 10 分钟内从 25°C 升至 68.3°C。