牙源性牙龈上皮错构瘤，具有多形性组织学表现：病例报告及文献复习。

Odontogenic gingival epithelial hamartoma with a pleomorphic histological appearance: a case report and review of the literature.

机构信息

Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Department of Oral Pathology, Unit of Basic Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

出版信息

Int J Oral Maxillofac Surg. 2021 Sep;50(9):1182-1186. doi: 10.1016/j.ijom.2021.01.007. Epub 2021 Feb 12.

DOI:10.1016/j.ijom.2021.01.007

PMID:33583664

Abstract

Odontogenic gingival epithelial hamartoma (OGEH) is a rare odontogenic epitheliallesion. Distinguishing OGEH from peripheral ameloblastoma can pose a differential diagnostic challenge. We report a case of OGEH affecting the lower gingiva in a 78-year-old male patient. The lesion presented as a large, painless, pedunculated mass with a pleomorphic histological appearance. A diagnosis of OGEH was made after the exclusion of peripheral ameloblastoma and peripheral adenomatoid odontogenic tumour. Previous studies have reported differences in sex and age between patients with OGEH and peripheral ameloblastoma; this suggests that peripheral ameloblastoma is not derived from OGEH. Histological findings suggest that the lesions are independent entities.

摘要

牙源性牙龈上皮错构瘤（OGEH）是一种罕见的牙源性上皮病变。将 OGEH 与外周性成釉细胞瘤区分开来可能具有鉴别诊断挑战性。我们报告了一例发生于 78 岁男性患者的下牙龈 OGEH。病变表现为无痛性、有蒂的大型多形性肿块。在排除外周性成釉细胞瘤和外周性腺瘤样牙源性肿瘤后，诊断为 OGEH。先前的研究报告了 OGEH 和外周性成釉细胞瘤患者在性别和年龄上的差异；这表明外周性成釉细胞瘤不是源自 OGEH。组织学发现表明这些病变是独立的实体。